| Interacting proteins: Q08881 and P42768 |
Pubmed |
SVM Score :0.0 |
| Under conditions of increased detergent stringency Sam 68 , Wiskott Aldrich Syndrome protein , and hnRNP K , but not Cbl and Fyn , were bound to the Itk SH 3 domain . ^^^ By examining the ability of different SH 3 domains to interact with deletion variants of Sam 68 and WASP , we demonstrated that the Itk SH 3 domain and the SH 3 domains of Src family kinases bind to overlapping but distinct sets of proline rich regions in Sam 68 and WASP . . ^^^ |
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| Interacting proteins: Q08881 and P42768 |
Pubmed |
SVM Score :0.0 |
| In this work , we show binding of WASP to the Src homology 3 domains of Btk , Itk , Tec , Grb 2 , and phospholipase C gamma , which suggests a function for WASP in lymphoid cell signaling . . ^^^ |
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| Interacting proteins: Q08881 and P42768 |
Pubmed |
SVM Score :0.0 |
| Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc 42 and WASP . ^^^ |
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