Interacting proteins: P42768 and P19174 |
Pubmed |
SVM Score :0.0 |
In addition , the reconstituted WASP interacted in vitro with proteins containing SH 3 domain such as Grb 2 , PLC gamma 1 , and Fyn , each of which are connected to signaling pathways linked to the actin cytoskeleton . ^^^ |
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Interacting proteins: P42768 and P19174 |
Pubmed |
SVM Score :0.0 |
Absence of WASp results in decreased accumulation of calcineurin , WASp interacting protein , and molecules upstream of calcium mobilization , i . e . , activated ZAP 70 and phospholipase C gamma 1 , in the disorganized NK cell immune synapse . ^^^ |
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Interacting proteins: P42768 and P19174 |
Pubmed |
SVM Score :0.0 |
As protein tyrosine phosphorylation is thought to represent a proximal event in the activation of B cells , inducing increases in [ Ca2+ ] 1 by virtue of tyrosine phosphorylation of phospholipase C ( PLC ) gamma , profiles of protein tyrosine phosphorylation and expression of tyrosine phosphorylated PLC gamma 1 were compared between WAS and normal EBV B cells before and after sIg cross linking . ^^^ These studies revealed that in addition to defective mobilization of Ca2+ , the WAS cells manifested little or no increase in tyrosine phosphorylation of PLC gamma 1 or other intracellular proteins after sIg ligation . ^^^ |
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Interacting proteins: P42768 and P19174 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: P42768 and P19174 |
Pubmed |
SVM Score :0.0 |
NA |
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