| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| In this study , we compared expression levels of messenger RNAs ( mRNAs ) encoding the epidermal growth factor ( EGF ) receptor related receptor tyrosine kinases ( ErbB 1 through 4 ) , the six EGF receptor ligands , EGF , transforming growth factor ( TGF ) alpha , amphiregulin ( ARG ) , HB EGF , betacellulin , and epiregulin , and the related molecule heregulin alpha , in a series of 10 prostate tissue specimens . ^^^ ARG was immunolocalized largely to interstitial smooth muscle cells ( SMC ) , previously identified as the site of synthesis of HB EGF in the prostate , while the cognate ARG and HB EGF receptor , ErbB 1 , was localized exclusively to ductal epithelial cells and carcinoma cells . ^^^ |
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| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| SELH / Bc , Abl / Arg , Mena / Profilin 1 ) . ^^^ The genes mutated in several mouse NTD models involve actin regulation ( Abl / Arg , Macs , Mena / Profilin1 , Mlp , Shrm , Vcl ) , support the postulated key role of actin in neural fold elevation , and may be a good candidate pathway to search for human NTD genes . . ^^^ |
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| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| The regions responsible for this poor binding are known to be Arg ( 45 ) in hEGF and the L 2 domain in the chicken EGFR . ^^^ |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| Chemical modification of EGFR JM by using arginine selective phenylglyoxal or deletion of the basic segment Arg ( 645 ) Arg ( 657 ) inhibits the interaction . ^^^ |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| The RBD , expressed as a peptide , binds at nM concentrations to HER 2 , the EGFR , DeltaEGFR , HER 4 and to the IGF 1 receptor , but not to HER 3 nor to the FGF 3 receptor , whereas a rare mutation in the RBD ( Arg to Ile ) eliminates receptor binding . ^^^ |
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| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| CONCLUSION : The data suggest that constitutively upregulated autocrine / paracrine secretion of EGF receptor ligands , especially ARG from K Ras mutated cells , mediates radioresistance in Rasmt cells through stimulation of EGFR PI3K AKT pathway . . ^^^ |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42684 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|