| Interacting proteins: P30622 and P42345 |
Pubmed |
SVM Score :0.0 |
| The FKBP 12 rapamycin associated protein ( FRAP ) is a CLIP 170 kinase . ^^^ In this study , we show that FKBP 12 rapamycin associated protein ( FRAP , also called mTOR / RAFT ) interacts with CLIP 170 . ^^^ CLIP 170 is phosphorylated in vivo at multiple sites , including rapamycin sensitive and insensitive sites , and is phosphorylated by FRAP in vitro at the rapamycin sensitive sites . ^^^ Our observations suggest that multiple CLIP 170 kinases are involved in positive and negative control of CLIP 170 , and FRAP is a CLIP 170 kinase positively regulating the MT binding behavior of CLIP 170 . . ^^^ |
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| Interacting proteins: P30622 and P42345 |
Pubmed |
SVM Score :0.0 |
| Down regulation of CLIP 170 , a putative mTOR substrate with microtubule binding properties , rescued the abnormal microtubule arrangement and caveolin 1 localization in Tsc 2 / cells . ^^^ |
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