| IL 2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3 ' kinase / Akt , heat shock protein 90 , and mammalian target of rapamycin in transformed NK cells . ^^^ Immunoprecipitates of Akt , Hsp 90 , mTOR , and S6K from IL 2 stimulated NK 92 cells contained telomerase activity . ^^^ Furthermore , the findings that Hsp 90 and mTOR immunoprecipitates from primary samples contained telomerase activity are consistent with the results from NK 92 cells . ^^^ |