| Interacting proteins: P41594 and P62158 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 ( mGluR 5 ) are antagonistic in vitro . ^^^ We herein report that calmodulin ( CaM ) interacts with the metabotropic glutamate receptor subtype 5 ( mGluR 5 ) in a Ca2+ dependent manner in vitro . ^^^ The CaM binding domains are separated by an alternatively spliced exon cassette present in one of the splicing isoforms of mGluR 5 . ^^^ |
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| Interacting proteins: P41594 and P62158 |
Pubmed |
SVM Score :0.0 |
| Finally , overexpression of wild type calmodulin , which can bind mGluR 5 and inhibit phosphorylation , did not alter mGluR desensitization . ^^^ These data indicate a role for nonconventional protein kinase C isoforms as a mediator of mGluR 5 desensitization and that the phosphorylation of mGluR5a that competes with calmodulin binding does not mediate desensitization . . ^^^ |
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| Interacting proteins: P41594 and P62158 |
Pubmed |
SVM Score :0.0 |
| We used antibodies against the following proteins and amino acids : the neurotransmitters glutamate and gamma aminobutyric acid ( GABA ) ; the GABA synthesizing enzyme glutamic acid decarboxylase ( GAD ) ; GABA transporter 1 ; the anchoring protein for GABA and glycine receptors , gephyrin ; the calcium binding proteins calbindin and calretinin ; the NR 1 subunit of the N methyl D aspartate glutamate receptor ; the metabotropic glutamate receptors mGluR1alpha , mGluR2 / 3 , and mGluR 5 ; and the intracellular signaling molecules calcineurin , calcium calmodulin kinase IIalpha ( CAMKIIalpha ) and the receptor for inositol triphosphate ( IP3R1alpha ) . ^^^ |
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| Interacting proteins: P41594 and P62158 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P41594 and P62158 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41594 and P62158 |
Pubmed |
SVM Score :0.0 |
| NA |
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