| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.59830542 |
| In contrast , association of Csk with caveolin 1 was completely dependent on phosphorylation of caveolin 1 , both for fusion proteins in yeast ( > 35 fold difference in affinity ) and for endogenous proteins in tissue culture cells . 0.59830542^^^ |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :1.161903 |
| Csk binds specifically to the phosphorylated caveolin 1 and attenuates its stress induced phosphorylation . 1.161903^^^ |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| The findings point to an antioncogenic role for CD 99 in osteosarcoma , likely through the regulation of caveolin 1 and inhibition of c Src kinase activity . . ^^^ |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Integrin mechanotransduction stimulates caveolin 1 phosphorylation and recruitment of Csk to mediate actin reorganization . ^^^ In manipulating Src family kinase ( SFK ) activity with knockdown of Csk or type 1 protein phosphatase ( PP 1 ) treatment , we observed coordinate increase and decrease in shear induced caveolin 1 phosphorylation , respectively . ^^^ Csk , described to interact with pY 14 caveolin 1 and integrins , bound to an increased pool of phosphorylated caveolin 1 after shear corresponding with elevated Csk at beta 1 integrin sites . ^^^ Like caveolin 1 , treatment with JB1A and PP 1 attenuated shear induced Csk association with beta 1 integrins . ^^^ Csk function was assayed with transfection of a caveolin 1 phosphorylation domain peptide . ^^^ |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Pharmacological studies demonstrated that , among these pathways , only the blockade of CSK activation abolished H ( 2 ) O ( 2 ) induced CAV 1 phosphorylation . ^^^ |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
|