We show that hnRNP K and the c Src kinase specifically interact with each other , leading to c Src activation and tyrosine phosphorylation of hnRNP K in vivo and in vitro . c Src mediated phosphorylation reversibly inhibits the binding of hnRNP K to the differentiation control element ( DICE ) of the LOX mRNA 3 ' untranslated region in vitro and specifically derepresses the translation of DICE bearing mRNAs in vivo . 1.0363897^^^ |