| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| VEGF stimulation specifically activated c Src kinase activity but not that of other related Src kinases such as Lyn , Fyn , or Hck in KS cells . ^^^ |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| Finally , overexpression of STAT 3 in Rat 2 cells transiently stimulated Hck and c Src kinase activity in the absence of extracellular signals , an effect that was dependent upon a putative SH 3 binding motif in STAT 3 . ^^^ |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| CHK / HYL did not affect the activity of Src , Hck , and Fgr in cultured bone marrow cells , although CSK negatively regulates Src family kinases . ^^^ |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| The polypeptide chain fold of CSK is most similar to c Src , Hck and fibroblast growth factor receptor 1 kinase ( FGFR1K ) and most dissimilar to insulin receptor kinase ( IRK ) . ^^^ |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| Constitutive exclusion of Csk from Hck positive membrane microdomains permits Src kinase dependent proliferation of Theileria transformed B lymphocytes . ^^^ Proliferation arrest led to a striking increase of PAG / Cbp expression ; correspondingly , the amount of Csk associated with PAG / Cbp in GEMs increased markedly , whereas PTK Hck accumulation in GEM fractions did not alter on growth arrest . ^^^ We propose that Theileria induced lymphocyte proliferation and permanent activation of Hck stems from down regulation of PAG / Cbp and the concomitant constitutive loss of the negative regulator Csk from the GEMs of transformed B cells . . ^^^ |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| In Saccharomyces cerevisiae , which lacks the negative regulatory tail kinase Csk , wild type Hck was more strongly activated in the presence of an SH 3 binding protein ( human immunodeficiency virus 1 Nef ) , indicating persistence of native SH 3 linker interaction in an active Hck conformation . ^^^ |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41240 and P08631 |
Pubmed |
SVM Score :0.0 |
| NA |
|