| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| We showed that EP receptor agonists ( PGE 1 ) EP2 / EP3 agonist ( misoprostol ) , EP 2 receptor agonist ( butaprost ) and DP receptor agonist ( PGD 2 ) inhibited fMLP stimulated superoxide production from human blood neutrophils in a concentration dependent manner . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| Since PGD 2 and 17 phenyl omega trinor PGE 2 ( EP 1 agonist ) did not suppress TNF alpha generation , the EP1 / EP2 / DP receptor antagonist , AH 6809 , was employed to assess if EP 2 receptors mediated the inhibitory effect of PGE 2 . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| A high degree of homology between the four Gs coupled prostaglandin ( PG ) receptors [ EP 2 , EP 4 , prostacyclin ( IP ) , PGD 2 ( DP ) ] and the four Gq / Gi coupled receptors [ EP 1 , EP 3 , PGF2alpha ( FP ) , thromboxane A 2 ( TP ) ] suggests that prostaglandin receptors evolved functionally from an ancestral EP receptor before the development of distinct binding epitopes . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| Administration of nonselective COX inhibitor ibuprofen or COX 2 inhibitor nimesulide every 8 h for 24 h to newborn rats and pigs reduced prostaglandin levels and caused comparable reductions in nNOS mRNA , protein , and activity to levels of adults ; COX inhibitor induced changes were prevented by cotreatment with PGE 2 analog , 16 , 16 dimethyl PGE 2 , and agonist for the EP 3 receptor of PGE 2 , sulprostone , but not by PGI 2 analog carbaprostacyclin , PGD 2 , EP 1 receptor agonist 17 phenyl trinor PGE 2 , and EP 2 agonist butaprost . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| Increases in CGRP levels were also observed in response to prostaglandin D 2 ( PGD 2 ) , and the EP 2 receptor selective agonist , butaprost . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| Examination of prostanoid receptors using bath perfusions ( 1 microM PGE 2 and PGD 2 ) , specific agonists ( BW245C , sulprostone , and butaprost ) , and antagonists ( AH 6809 and SC 19220 ) found evidence for both the PGE 2 specific EP 2 and EP 3 receptors , but not for EP 1 or the PGD 2 specific prostanoid ( DP ) receptors . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| To clarify the uterine region dependent distribution of prostanoid receptors , we compared the mechanical responses to selective prostanoid receptor agonists ( FP , EP 3 , DP , EP 2 ) and naturally occurring prostaglandins ( PGF2alpha PGE 2 , PGD 2 ) in longitudinal and circular muscles isolated from three different regions ( cornu , corpus and cervix ) of the non pregnant porcine uterus . ^^^ |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41222 and P43116 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| A high degree of homology between the four Gs coupled prostaglandin ( PG ) receptors [ EP 2 , EP 4 , prostacyclin ( IP ) , PGD 2 ( DP ) ] and the four Gq / Gi coupled receptors [ EP 1 , EP 3 , PGF2alpha ( FP ) , thromboxane A 2 ( TP ) ] suggests that prostaglandin receptors evolved functionally from an ancestral EP receptor before the development of distinct binding epitopes . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| Administration of nonselective COX inhibitor ibuprofen or COX 2 inhibitor nimesulide every 8 h for 24 h to newborn rats and pigs reduced prostaglandin levels and caused comparable reductions in nNOS mRNA , protein , and activity to levels of adults ; COX inhibitor induced changes were prevented by cotreatment with PGE 2 analog , 16 , 16 dimethyl PGE 2 , and agonist for the EP 3 receptor of PGE 2 , sulprostone , but not by PGI 2 analog carbaprostacyclin , PGD 2 , EP 1 receptor agonist 17 phenyl trinor PGE 2 , and EP 2 agonist butaprost . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| Increases in CGRP levels were also observed in response to prostaglandin D 2 ( PGD 2 ) , and the EP 2 receptor selective agonist , butaprost . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| Examination of prostanoid receptors using bath perfusions ( 1 microM PGE 2 and PGD 2 ) , specific agonists ( BW245C , sulprostone , and butaprost ) , and antagonists ( AH 6809 and SC 19220 ) found evidence for both the PGE 2 specific EP 2 and EP 3 receptors , but not for EP 1 or the PGD 2 specific prostanoid ( DP ) receptors . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| To clarify the uterine region dependent distribution of prostanoid receptors , we compared the mechanical responses to selective prostanoid receptor agonists ( FP , EP 3 , DP , EP 2 ) and naturally occurring prostaglandins ( PGF2alpha PGE 2 , PGD 2 ) in longitudinal and circular muscles isolated from three different regions ( cornu , corpus and cervix ) of the non pregnant porcine uterus . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| We showed that EP receptor agonists ( PGE 1 ) EP2 / EP3 agonist ( misoprostol ) , EP 2 receptor agonist ( butaprost ) and DP receptor agonist ( PGD 2 ) inhibited fMLP stimulated superoxide production from human blood neutrophils in a concentration dependent manner . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| Since PGD 2 and 17 phenyl omega trinor PGE 2 ( EP 1 agonist ) did not suppress TNF alpha generation , the EP1 / EP2 / DP receptor antagonist , AH 6809 , was employed to assess if EP 2 receptors mediated the inhibitory effect of PGE 2 . ^^^ |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43116 and P41222 |
Pubmed |
SVM Score :0.0 |
| NA |
|