| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| In a group of 23 obese women the relations between some indicators of thyroid function ( thyroxine binding globuline T4BG , triiodothyronine binding globuline T3BG , Achilles tendon reflex ART ) on the one hand and activities of enzymes of the energy metabolism ( hexokinase HK , triose phosphate dehydrogenase TPDH , lactate dehydrogenase LDH , glycerol 3 phosphate dehydrogenase GPDH , citrate synthease CS , malate dehydrogenase MDH , hydroxyacyl COA dehydrogenase ) in the quadriceps femoris muscle on the other hand were investigated . 2 . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The enzymes were : Hexokinase ( HK ) , NAD : glycerol 3 phosphate dehydrogenase ( GPDH ) , triosephosphate dehydrogenase ( TPDH ) , lactate dehydrogenase ( LDH ) , citrate synthase ( CS ) , NAD : malate dehydrogenase ( MDH ) , and 3 hydroxyacyl CoA dehydrogenase ( HOADH ) . ^^^ In the intensively trained `` athletic ' ' group , enzymes connected to aerobic oxidation ( MDH , CS , HOADH ) and GPDH also show higher activities than in the `` sporting ' ' group . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The following enzyme activities were estimated in needle biopsy samples of the lateral part of the human quadriceps femoris muscle : triosephosphate dehydrogenase ( TPDH ) , lactate dehydrogenase ( LDH ) , NAD : glycerol 3 phosphate dehydrogenase ( GPDH ) , hexokinase ( HK ) , NAD : malate dehydrogenase ( MDH ) , citrate synthase ( CS ) and hydroxyacyl CoA dehydrogenase . 2 . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| In biopsy samples of the lateral part of m . quadriceps femoris of 49 obese and 14 lean persons the activities of the following enzymes were investigated : triosephosphate dehydrogenase ( TPDH ) , glycerolphosphate : nad dehydrogenase ( GPDH ) , lactate dehydrogenase ( LDH ) , hexokinase ( HK ) , malate : NAD dehydrogenase ( MDH ) , citrate synthase ( CS ) and hydroxyacyl CoA dehydrogenase ( HOADH ) . 2 . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The other enzyme activities associated with anaerobic glycolysis ( TPDH , GPDH ) and those linked up in aerobic metabolism ( MDH , CS ) did not change significantly . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The activity of 7 mitochondrial enzymes , fumarase , NAD malate dehydrogenase ( MDH ) , citrate synthase ( CS ) , valine dehydrogenase ( VDH ) , succinate dehydrogenase ( SDH ) , glutamate dehydrogenase ( GDH ) , pyruvate dehydrogenase complex ( PDHC ) has been measured in platelet preparations from patients affected by Friedreich ' s ataxia ( FA ) , dominant and non dominant olivopontocerebellar atrophy ( DOPCA , NDOPCA ) and normal individuals . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The patterns of training induced increases in CS , MDH and HAD indicate that the levels of these enzymes can be regulated independently . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Some brains were prepared histochemically for the mitochondrial enzymes cytochrome oxidase ( CO ) and succinic dehydrogenase ( SDH ) , and some were prepared for microchemical analysis of the enzymes citrate synthase ( CS ) , malate dehydrogenase ( MDH ) and phosphorylase . ^^^ The oxidative enzymes ( CO , SDH , CS and MDH ) that were analyzed by histochemical and microchemical approaches showed a decrease in activities as early as 3 weeks postdeafferentation , a trend that continued up to 12 weeks in all the subcortical trigeminal stations and lateral geniculate nucleus ( LGN ) when compared with the intact side . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Changes in the activity levels of hexokinase ( HK ) , phosphofructokinase ( PFK ) , glyceraldehydephosphate dehydrogenase ( GAPDH ) , lactate dehydrogenase ( LDH ) , creatine kinase ( CK ) , citrate synthase ( CS ) , malate dehydrogenase ( MDH ) , 3 hydroxyacyl CoA dehydrogenase ( HADH ) , and beta hydroxybutyrate dehydrogenase ( HBDH ) were compared . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Maximal activities of rat skeletal muscle mitochondrial citrate synthase ( CS ) , malate dehydrogenase ( MDH ) , and alanine aminotransferase ( ALT ) , as well as several other mitochondrial enzymes involved in various metabolic functions were significantly suppressed after a single bout of acute or exhaustive treadmill running . ^^^ Decreased CS , MDH , and ALT activities correlated with a significant loss of mitochondrial total protein sulfhydryl ( r = 0 . 67 , 0 . 68 , 0 . 59 , respectively , P less than 0 . 001 ) in untrained rats and both CS and MDH could be partially restored by incubation with dithiothreitol . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| In both groups the type 1 fibres exhibited higher levels of the TCA cycle marker enzyme citrate synthase ( CS ) , as well as of the malate aspartate shuttle enzymes ( cytoplasmic and mitochondrial malate dehydrogenase ( cMDH , mMDH ) , and aspartate aminotransferase ( cASAT , mASAT ] . ^^^ A more pronounced difference between type 1 and type 2 fibres was noted for cMDH ( 58 % ) than for mMDH ( 16 % ) , cASAT ( 20 % ) , mASAT ( 18 % ) and CS ( 25 % ) . ^^^ In the endurance trained group , both fibre types were characterized by higher levels of CS ( mean for both fibre types : 48 % ) as well as of mitochondrial malate aspartate shuttle enzymes ( mMDH : 47 % , mASAT : 48 % ) than in the corresponding fibre types in the untrained group , while the differences in the levels of cytoplasmic malate aspartate shuttle enzymes ( cMDH : 13 % , cASAT : 16 % ) were not statistically significant . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| None of the treatments used had influence on the activities of myocardial enzymes : 3 hydroxyacyl CoA dehydrogenase ( HADH ) , succinate dehydrogenase ( SDH ) , malate dehydrogenase ( MDH ) , and citrate synthase ( CS ) which were assayed for estimating oxidative capacity , or lactate dehydrogenase ( LDH ) which was used as a measure of anaerobic capacity . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Enzymes representing glycolytic ( phosphofructokinase ( PFK ] and mitochondrial ( citrate synthase ( CS ) and malate dehydrogenase ( MDH ] metabolisms were evaluated . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Although some variations occurred , the enzyme profiles were characteristic of those of the nervous tissue from the second day of life onwards until adulthood and displayed relatively high activities of HK , CS and MDH and low activities of TPDH , LDH , GPDH and HOADH . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The enzymes were selected in such a manner , as to characterize most of the main metabolic pathways of energy supplying metabolism : hexokinase ( glucose phosphorylation , HK ) , glycerol 3 phosphate dehydrogenase ( glycerolphosphate metabolism or shunt , GPDH ) , triose phosphate dehydrogenase ( glycolytic carbohydrate breakdown , TPDH ) , lactate dehydrogenase ( lactate metabolism , LDH ) , citrate synthase ( tricarboxylic acid cycle , aerobic metabolism , CS ) , malate NAD dehydrogenase ( tricarboxylic acid cycle , intra extra mitochondrial hydrogen transport , MDH ) and 3 hydroxyacyl CoA dehydrogenase ( fatty acid catabolism , HOADH ) . 2 . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| In the EDL , the activity of triosephosphate dehydrogenase ( TPDH ) , GPDH , malate dehydrogenase ( MDH ) , CS and HOADH was decreased . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Using quantitative methods , citrate synthase ( CS ) , fumarase , beta hydroxyacyl coenzyme A ( CoA ) dehydrogenase ( beta OAC ) , 3 keto acid CoA transferase ( KCT ) , malic dehydrogenase ( MDH ) , and malic enzyme were measured in seven defined parts of the nephron and in thin limb and papilla areas dissected from freeze dried microtome sections of rat kidney . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The enzymes used as markers of different pathways of energy liberation from substrates were : lactate dehydrogenase LDH ( EC 1 . 1 . 1 . 27 ) , triose 3 phosphate dehydrogenase TPDH ( EC 1 . 2 . 1 . 12 ) , glycerol 3 phosphate dehydrogenase GPDH ( EC 1 . 1 . 1 . 8 ) , hexokinase HK ( EC 2 . 7 . 1 . 1 . ) , malate : NAD dehydrogenase MDH ( EC 1 . 1 . 1 . 37 ) , citrate synthase CS ( EC 4 . 1 . 3 . 7 ) , and 3 hydroxyacetyl CoA dehydrogenase HOADH ( EC 1 . 1 . 1 . 35 ) . ^^^ However , all the aggregates exhibited `` profiles ' ' characteristic for the nervous tissue , with relatively very high activity of HK , high activity of MDH and CS ( carbohydrate breakdown ) and low activity of GPDH and HOADH ( lipid catabolism ) . . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| There were parallel increases in citrate synthase ( CS ) and malate dehydrogenase ( MDH ) during the first 3 weeks of training ( 30 % ) . ^^^ CS then continued to rise ( to 90 % above pretraining level ) , while the increase in MDH levelled off . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Peak VO 2 on the bicycle ergometer , VO2max during graded treadmill running and concentrations of citrate synthase ( CS ) and malate dehydrogenase ( MDH ) in the vastus lateralis muscle were measured before and after training . ^^^ Endurance training elicited significant increases in peak VO 2 ( 36 % ) , VO2max ( 32 % ) , CS ( 25 % ) and MDH ( 42 % ) ( all P less than 0 . 05 ) . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Activity levels of citrate synthetase ( CS ) , malate dehydrogenase ( MDH ) , succinate dehydrogenase ( SDH ) , 3 hydroxy acyl CoA dehydrogenase ( HAD ) , and lactate dehydrogenase ( LDH ) were determined quantitatively by either microbiochemical assays ( CS , MDH , HAD and LDH ) on microdissected , single fibres or by kinetic microphotometry on cross sectioned fibres ( SDH ) . ^^^ Despite a several fold increase in the activities of CS , MDH , SDH and HAD and a pronounced decrease in LDH , chronic stimulation failed to abolish the metabolic heterogeneity of the fibre population . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Changes in the activity of muscle enzymes of energy metabolism were studied in two groups of skiers ( A , B ) with a different sports performance ( triosephosphate dehydrogenase TPDH , lactate dehydrogenase LDH , glycerol 3 phosphate dehydrogenase GPDH , hexokinase HK , malate dehydrogenase MDH , citrate synthase CS , hydroxyacyl , CoA dehydrogenase HOADH ) . 1 . ^^^ In a group of ski runners ( A ) significantly higher activities of CS , MDH , HOADH in the preparatory period ( October ) and also at the end of the competition period ( March ) were found in athletes with higher sports performance . 2 . ^^^ Significantly lower activities of LDH , GPDH , MDH , CS , HOADH were found in downhill skiers ( group B ) . 3 . ^^^ Some significant correlations were established , both between the activities of individual enzymes ( TPDH , GPDH , HK , CS , HOADH ) and between the enzymes and indicators of functional capacity ( MDH , CS , HOADH , VO2max , HRmax , O 2 pulse max , body fat , laboratory performance ) . . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Succinate dehydrogenase ( SDH ) , malate dehydrogenase ( MDH ) , citrate synthase ( CS ) and lactate dehydrogenase ( LDH ) were analyzed biochemically and percentage of slow twitch fibres ( % ST fibres , myosin adenosine triphosphatase staining ) histochemically in muscle samples obtained from m . vastus lateralis . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Acute pancreatitis caused an increase in lipofuscin accumulation , and a decrease in protein sulfhydryl groups in citrate synthetase ( CS ) and in malate dehydrogenase ( MDH ) activity . ^^^ |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The lactate dehydrogenase ( LDH ) activity in BM showed significantly lower values than that in BR , whereas citrate synthase ( CS ) and malate dehydrogenase ( MDH ) activities were remarkably higher in BM . ^^^ While BM showed decrease of G6PD and LDH activities at day 19 a . i . , it showed remarkably increased activities in CS and MDH ( 368 and 8 , 842 nmol / min . mg protein , respectively ) . ^^^ Although CS and MDH activities also showed a slight increase at day 12 a . i . , the activities of PDH , ICDH , KGDH and SDH did n ' t change from day 9 to 12 a . i . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The activities of NADH cytochrome c reductase ( NCCR ) , cytochrome oxidase ( CO ) , citrate synthase ( CS ) and malate dehydrogenase ( MDH ) were measured in whole tissue homogenates and in mitochondrial preparations of separated bladder mucosa and muscle , from normal bladders , and , from hypertrophied bladders at 1 , 3 , and 7 days following partial outlet obstruction . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| In TTX PL macro samples , activities of glycerol 3 phosphate dehydrogenase ( GPDH ) , pyruvate kinase ( PK ) , malate dehydrogenase ( MDH ) , citrate synthase ( CS ) , beta hydroxyacyl CoA dehydrogenase ( BOAC ) , and thiolase were , or tended to be , lower . ^^^ In TTX Sol macro samples , GPDH and PK tended to be higher , and thiolase , BOAC , CS , and MDH lower . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Mitochondrial enzyme activities ( cytochrome c oxidase = COX , carnitine acyl transferase = CAT , citrate synthase = CS , lipoamide dehydrogenase = lipDH from the pyruvate dehydrogenase complex , lactate dehydrogenase = LDH , and malate dehydrogenase = MDH ) were measured from progressive myopathy / encephalomyopathy . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The diffusion of oxaloacetate from one of the active sites of malate dehydrogenase ( MDH ) to the active sites of citrate synthase ( CS ) was simulated in the presence and absence of electrostatic forces using a modeled structure for a MDH CS fusion protein . ^^^ In the absence of electrostatic forces , fewer than 1 % of substrate molecules leaving the MDH active site are transferred to CS . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| These experiments use the sequential Krebs TCA cycle enzymes from yeast mitochondrial malate dehydrogenase ( MDH ) , citrate synthase ( CS ) , and aconitase ( ACO ) . ^^^ This structure also contains an unbroken electrostatically favorable channel connecting the active sites of ACO and CS , as well as the one previously reported between CS and MDH active sites . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The activities of 5 key regulatory enzymes in most energetic systems , namely citrate synthase ( EC 4 . 1 . 3 . 7 , CS ) , NADP specific isocitrate dehydrogenase ( EC 1 . 1 . 1 . 42 , ICDH ) , succinate dehydrogenase ( EC 1 . 3 . 99 . 1 , SDH ) , L malate dehydrogenase ( EC 1 . 1 . 1 . 37 , MDH ) , and decarboxylating malic enzyme ( EC 1 . 1 . 1 . 40 , ME ) , were measured during the growth and metacyclogenesis of a cutaneous ( CL ) and a visceral ( VL ) strain of Leishmania infantum . ^^^ Both strains showed higher levels of CS , ICDH , and MDH and lower SDH and ME activities when more metacyclic promastigotes were present , but in VL these changes paralleled an increase in glucose consumption , whereas in CL these changes coincided with an NH 3 hyperproduction . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Citrate synthase ( CS ) , 3 hydroxyacyl CoA dehydrogenase ( HADH ) , and malate dehydrogenase ( MDH ) activities were measured in six hindlimb muscles . ^^^ However , no significant correlation was found between RTF and CS , HADH , or MDH in any muscle of the three groups of animals . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The following enzymes were assayed in the right and left ventricular myocardium : lactate dehydrogenase ( LDH , lactate uptake and / or formation ) , triose phosphate dehydrogenase ( TPDH , carbohydrate metabolism ) , glycerol phosphate dehydrogenase ( GPDH , glycerol P shuttle ) ) , hexokinase ( HK , glucose phosphorylation ) , malate dehydrogenase ( MDH , tricarboxylic cycle ) , citrate synthase ( CS , tricarboxylic cycle ) and hydroxyacyl CoA dehydrogenase ( HOADH , fatty acid breakdown ) . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| To demonstrate the power of the methodology , simulations have been conducted on an artificial fusion protein of citrate synthase ( CS ) and malate dehydrogenase ( MDH ) to assess the chances of oxaloacetate being channeled between the MDH and CS active sites . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| The present paper reports tissue enzyme levels of LDH , MDH , and CS , and isozymic tissue distribution of LDH , MDH , ADH , PGI , SOD , and PGM of 7 aestivating specimens from Lago do Canteiro in the Amazonas River . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Activities of citrate synthase ( CS ) , alpha ketoglutarate dehydrogenase ( KGDH ) and malate dehydrogenase ( MDH ) were threefold decreased . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Using an immobilized nardilysin column , mitochondrial malate dehydrogenase ( mMDH ) and citrate synthase ( CS ) were isolated from a fractionated rat brain extract . ^^^ CS was co immunoprecipitated with mMDH only in the presence of nardilysin showing that nardilysin facilitates complex formation . . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Deep water trawling was used to collect eels for studies of animal distribution and for anatomical and biochemical analyses , including white muscle citrate synthase ( CS ) , lactate dehydrogenase ( LDH ) , malate dehydrogenase ( MDH ) , and pyruvate kinase ( PK ) activities . ^^^ Activities of CS , LDH , MDH , and PK were higher than expected , and all scaled negatively with body mass , indicating a general decrease in muscle energy supply with fish growth . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| Ten fish of each species were exposed to graded hypoxia for 8 h in seven oxygen concentrations ( 5 . 92 , 3 . 15 , 1 . 54 , 0 . 79 , 0 . 60 , 0 . 34 , and 0 . 06 mg O ( 2 ) L ( ) ( 1 ) ) , with the aim to evaluate hypoxia tolerance and metabolic adjustments , where plasma glucose and lactate levels , hepatic and muscle glycogen contents , and maximum enzyme activities ( PK , LDH , MDH and CS ) in skeletal and cardiac muscles were measured . ^^^ |
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| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75390 and P40926 |
Pubmed |
SVM Score :0.0 |
| NA |
|