| Interacting proteins: Q03405 and P40189 |
Pubmed |
SVM Score :0.0 |
| We found that in the human kidney epithelial line TCL 598 , also components of the JAK1 / STAT1 signal transduction pathway including gp 130 , are associated with uPAR as revealed by coimmunoprecipitation and are co localized in caveolae . ^^^ Therefore , in this cell line , uPA . uPAR also utilizes the JAK1 / STAT1 pathway for signaling , and gp 130 might be the transmembrane adapter for this signal transduction pathway . . ^^^ |
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| Interacting proteins: Q03405 and P40189 |
Pubmed |
SVM Score :0.0 |
| The association of gp 130 with uPA may link the uPA uPAR system to various signal transduction pathways . . ^^^ |
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| Interacting proteins: Q03405 and P40189 |
Pubmed |
SVM Score :0.0 |
| This effect is mediated via the interaction of the uPA specific receptor ( uPAR , CD 87 ) and gp 130 , a signal transducing subunit of the receptor complexes for the IL 6 cytokine family . ^^^ |
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