| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| On IL 6 stimulation , SHP 2 and Gab 1 were recruited to the gp 130 subunit of the IL 6 receptor and tyrosine phosphorylated , allowing downstream signaling to the MAPK and PI3K pathways . ^^^ |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| The binding of cytokines to the gp 130 receptor activates the STAT 3 , MEK / MAPK , and PI3K / Akt signalling pathways . ^^^ |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| In addition , androgen treatment enhances the interaction between AR and gp 130 , interrupts the IL 6 induced gp 130 mediated PI3K activation , which may lead to inhibition of IL 6 mediated NE differentiation in LNCaP cells . ^^^ |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| The interleukin 6 ( IL 6 ) family of cytokines signals through the common receptor subunit gp 130 , and subsequently activates Stat 3 , MAPK , and PI3K . ^^^ |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| In addition , gp 130 activation leads to both PI3K and Src activation . ^^^ |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48736 and P40189 |
Pubmed |
SVM Score :0.0 |
| NA |
|