Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator activated receptor gamma transcriptional activity and repress 3T3 L 1 adipogenesis . ^^^ |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
The interaction between PPARgamma 2 and SMRT localized to the receptor interactive domain 2 ( amino acids 1260 1495 ) of the SMRT protein based on cotransfection and pull down assays . ^^^ These in vitro data indicate that COUP TF proteins and SMRT modulate PPARgamma mediated LPL transcription in the 293T cell line . . ^^^ |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
Furthermore , association of ERK5a and PPARgamma 1 disrupted the interaction of SMRT and PPARgamma 1 , thereby inducing PPARgamma activation . ^^^ |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
In contrast to PPARgamma , wild type PPARalpha failed to recruit the transcriptional corepressors NCoR and SMRT . ^^^ |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
A major difference among the three PPARgamma agonists was the higher activity of CDDO Im to induce PPARgamma interactions with the corepressor SMRT . ^^^ |
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Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
FK 614 dissociates the corepressors NCoR ( nuclear receptor corepressor ) and SMRT ( silencing mediator of retinoid and thyroid hormone receptors ) from PPARgamma as effectively as rosiglitazone and pioglitazone , but can also differentially induce a ligand specific interaction of PPARgamma with coactivators . ^^^ |
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Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
Recent evidence , however , suggests that NCoR and SMRT repress PPARgamma mediated transcriptional activity on specific promoters in the adipocyte . ^^^ |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P37231 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
NA |
|