| Interacting proteins: P37231 and Q04206 |
Pubmed |
SVM Score :0.0 |
| Peroxisome proliferator activated receptor gamma ( PPAR gamma ) , in complex with nuclear RelA , also undergoes nucleocytoplasmic redistribution in response to B . thetaiotaomicron . ^^^ |
|
| Interacting proteins: P37231 and Q04206 |
Pubmed |
SVM Score :0.0 |
| PPARgamma agonists activated NF kappaB ( p 50 , Rel A , c Rel ) binding to the upstream kappaB regulatory element site of c myc . ^^^ |
|
| Interacting proteins: P37231 and Q04206 |
Pubmed |
SVM Score :0.0 |
| In reporter gene assays in HeLa cells , ectopic expression of PPAR gamma abolished induction of a NF kappaB responsive reporter gene by the p 65 subunit ( RelA ) of NF kappaB , and the inhibition was further enhanced in the presence of TGZ . ^^^ |
|
| Interacting proteins: P37231 and Q04206 |
Pubmed |
SVM Score :0.0 |
| In addition , 15d PGJ ( 2 ) but not the synthetic high affinity PPARgamma ligand rosiglitazone triggered ERK1 / 2 phosphorylation in IEC , and most importantly , MEK 1 inhibitor PD 98059 reversed the inhibitory effect of 15dPGJ ( 2 ) on LPS induced RelA phosphorylation and interleukin 6 gene expression . ^^^ |
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