| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| CDDO Im induced the synthesis of mRNA for TGF beta 2 , BMP 6 , TGF beta type 2 receptor , and BMP type 2 receptor . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| In situ analysis of transforming growth factor beta s ( TGF beta 1 , TGF beta 2 , TGF beta 3 ) , and TGF beta type 2 receptor expression in malignant melanoma . ^^^ We have analysed , by in situ hybridization , mRNA expression of TGF beta 1 , TGF beta 2 , TGF beta 3 , and of TGF beta type 2 receptor in benign melanocytic naevi , primary melanomas , and in skin metastases of malignant melanomas . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Expression of TGF beta s and TGF beta type 2 receptor mRNAs in mouse folliculogenesis : stored maternal TGF beta 2 message in oocytes . ^^^ The present in situ hybridisation study describes expression of TGF beta 1 , TGF beta 2 , TGF beta 3 , and TGF beta type 2 receptor mRNA during follicular development , and the temporal pattern and abundance of TGF beta 2 transcripts in early pre implantation embryos . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Human uterine tissue throughout the menstrual cycle expresses transforming growth factor beta 1 ( TGF beta 1 ) , TGF beta 2 , TGF beta 3 , and TGF beta type 2 receptor messenger ribonucleic acid and protein and contains [ 125I ] TGF beta 1 binding sites . ^^^ The reverse transcription polymerase chain reaction revealed the predicted 443 , 310 , 524 , and 431 basepair fragments for TGF beta 1 , TGF beta 2 , TGF beta 3 , and TGF beta type 2 receptor , respectively , in both endometrial and myometrial tissues , which were further verified by restriction enzyme analysis . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Reverse transcription polymerase chain reaction analysis of total RNA and immunocytochemical observations revealed that human endometrial glandular epithelial and stromal cells in primary culture express messenger RNAs and proteins for transforming growth factor beta 1 ( TGF beta 1 ) , TGF beta 2 , and TGF beta 3 as well as TGF beta type 2 receptor . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| We demonstrate that primary cultured human thymic epithelial cells ( TEC ) express TGF beta 1 , TGF beta 2 and TGF beta 3 , as well as TGF beta type 1 receptor ( T beta RI ) ( ALK 5 ) and TGF beta type 2 receptor ( T beta RII ) transcripts . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| TGF beta 1 and TGF beta 2 mRNAs were expressed at higher levels in QTT T1C cells than in FRLE and TR T1C cells , and there was an increase in TGF beta type 2 receptor ( TGR betaR ) mRNA expression in QTT T1C and RT T1C cells compared to FRLE cells . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| The spatial and temporal patterns of expression of TGF beta 1 , TGF beta 2 , TGF beta receptor type 2 messenger RNAs ( mRNAs ) , and TGF beta 1 proteins in the different hepatic lesions suggests that TGF beta isoforms may play a role in the pathogenesis of quartz induced fibrosis , cirrhosis , liver cell adenoma , and carcinoma . . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Whereas expression of TGF beta 1 , TGF beta 2 , and TGF beta type 2 receptor was suppressed by glucocorticoids in normal and wounded skin , expression of TGF beta 3 and TGF beta receptor type 1 mRNA was stimulated . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| In situ analysis of transforming growth factors beta ( TGF beta 1 , TGF beta 2 , TGF beta 3 ) and TGF beta type 2 receptor expression in basal cell carcinomas . ^^^ In the present study , we have analysed and compared , by in situ hybridization , mRNA expression of transforming growth factors beta ( TGF beta 1 , TGF beta 2 , TGF beta 3 ) and TGF beta type 2 receptor ( T beta R 2 ) , and , by immunohistochemistry , the distribution of TGF beta 3 protein in normal human skin and in basal cell carcinoma ( BCC ) . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Furthermore , competition based quantitative reverse transcription PCR using synthetic internal standards revealed that leiomyomata express a significantly higher number ( copies per cell ) of TGF beta type 2 receptor mRNA , followed by TGF beta 1 , TGF beta type 1 receptor , TGF beta 2 , and TGF beta 3 ( P < 0 . 05 ) . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| In this study we have investigated the expression of the precursor forms of TGF beta 1 , TGF beta 2 , TGF beta 3 , as well as TGF beta type 1 receptor ( TGF betaRI ) and TGF beta type 2 receptor ( TGF betaRII ) in the synovial tissue of arthritic rats during the course of the disease . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| We have investigated the immunohistological localization of TGF beta 1 , TGF beta 2 , TbetaR 1 and TbetaR 2 in normal human skin , basal cell carcinoma ( BCC ) , Bowen ' s disease , seborrheic keratosis , eccrine poroma and eccrine spiradenoma using frozen tissue specimens . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| We show that CG neurons ( E 8 ) are immunoreactive ( ir ) for TGF beta 2 and beta 3 as well as the TGF beta receptor TbetaR 2 , but are not ir for TGF beta 1 . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Concomitant with this differentiation , expression of transforming growth factor beta 2 ( TGF beta 2 ) , TGF beta 3 , and TGF beta receptor type 2 ( TbetaRII ) is induced , while those of TGF beta 1 and TbetaRI remain essentially unchanged . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Northern blot analysis revealed enhanced expression ( P < 0 . 05 ) of TGF beta 1 ( twofold increase ) , TGF beta 2 ( threefold increase ) and TGF beta 3 ( 8 . 5 fold increase ) and of TbetaR 2 ( threefold increase ) mRNA in liver cirrhosis in comparison with normal controls . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| The expression and localization of TGF beta 1 , TGF beta 2 , TGF beta 3 , TbetaR IALK 5 , TbetaR 2 , and TbetaR 3 were studied by Northern blot analysis , in situ hybridization , and immunohistochemistry . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Expression of mRNAs for TGF beta 1 , TGF beta 2 , TGF beta receptor type 2 , and connective tissue growth factor ( CTGF ) was significantly greater in anterior polar type than in nuclear type cataracts . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Cryosections of these specimens were processed for immunohistochemical analysis for TGF beta 1 , TGF beta 2 , TGF beta 3 , TGF beta receptor type 1 ( TbetaR 1 ) , type 2 ( TbetaR 2 ) and type 3 ( TbetaR 3 ) , and were observed under light micros copy . ^^^ RESULTS : Lens epithelial cells ( LECs ) lining the inner surface of the anterior capsules exhibited immunoreactivity for TGF beta 2 and TbetaR 2 . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| We analyzed the mRNA expression of TGF beta 1 , TGF beta 2 , TGF beta 3 , the TGF beta receptors type 1 ( TbetaR 1 ) and type 2 ( TbetaR 2 ) , Smad 2 , Smad 3 , and Smad 4 . mRNA expression of IL 10 and CD 95 ( FAS / APO 1 ) were also studied . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| We therefore studied the expression of UPA , UPAR , IGF2R , ALK 5 ( TGFBR 1 ) , TGFBR 2 , TGFBR 3 , ENG , ALK 1 , TGFB 1 , TGFB 2 , and TGFB 3 in a series of 14 pancreatic carcinoma cell lines . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| The mRNA expressions of TGF beta 1 , TGF beta 2 and TGFRI were evidently increased with decreased mRNA expression of TGF beta 3 and TGFR 2 in the hypertrophic scar when compared with those in the normal skin . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| Inhibition of the ERK , p 38 kinase or JNK signal transduction pathways blocked the transcriptional up regulation of TGF beta 2 , TbetaR 1 , and TbetaR 2 in KKs . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| In the present study , we investigated the role of the three mammalian TGFbeta subtypes ( beta 1 , beta 2 , and beta 3 ) and their receptors ( type 3 ( TbetaR 3 ) , type 2 ( TbetaR 2 ) , and two types 1 ( TbetaR 1 ) , ALK 1 and ALK 5 ) in early rat lung organogenesis by using an embryonic rat lung explant culture . ^^^ Antisense inhibition of ALK 5 and TbetaR 2 showed a similar reduction in early lung branching as observed with antisense TGFbeta 2 . ^^^ |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P37173 |
Pubmed |
SVM Score :0.0 |
| NA |
|