| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| The protein interaction observed in yeast was further demonstrated by immunoprecipitation and Western blotting using purified intact TSP 1 , TSP 2 , MMP 2 , and MMP 9 . ^^^ |
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| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| This study was undertaken to quantitate mRNA levels in normal and malignant cervical tissues of nine selected genes ( VEGF ( 121 ) , VEGF ( 165 ) , VEGF ( 189 ) , VEGF C , eIF 4E , b FGF , TSP 2 , MMP 2 and MMP 9 ) implicated in the above processes using real time quantitative RT PCR . ^^^ |
|
| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| The transformants with the human TSP 2 gene overexpression showed a down regulation of matrix metalloproteinase 2 ( MMP 2 ) and MMP 9 in comparison to those with vector control . ^^^ Protein production of MMP 2 and MMP 9 decreased in the transformants overexpressing the TSP 2 gene . ^^^ |
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| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| At the same time , MMP 9 , thrombospondin 2 ( TSP 2 ) , etc . may play an important role in pulmonary cancer metastasis and infiltration . . ^^^ |
|
| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| In TSP 2 knockout mice , angiotensin 2 increased matrix metalloproteinase ( MMP ) 2 and MMP 9 activity by 120 % and 390 % compared with wild type mice ( P < 0 . 05 ) . ^^^ |
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| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| The present study was therefore designed to evaluate the expression of thrombospondin 1 and 2 ( TSP 1 , TSP 2 ) , TSP receptors CD 36 and CD 47 , and matrix metalloproteases 2 and 9 ( MMP , MMP 9 ) in a rat prostate cancer model . ^^^ By using immunohistochemistry , Western blot , and real time PCR the expression patterns of TSP 1 , TSP 2 , CD 36 , CD 47 , MMP 2 , and MMP 9 were investigated in normal rat prostate tissue and five malignant Dunning sublines tissue . ^^^ |
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| Interacting proteins: P35442 and P14780 |
Pubmed |
SVM Score :0.0 |
| We found elevated expression of MMP 2 and MMP 9 in tumors propagated in TSP 2 ( / ) mice , with a preferential localization in the microvasculature . ^^^ |
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