| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| COX 2 overexpression was detected in 69 % of the cases evaluated ( 24 / 35 ) , without significant association with TP 53 mutation . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| Here we report that the tumor suppressor p 53 upregulates COX 2 expression and that COX 2 can in turn inhibit p 53 dependent transcription . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| We sequenced BRAF and KRAS , analyzed for microsatellite instability ( MSI ) and 18q loss of heterozygosity ( LOH ) , and performed immunohistochemistry for TP 53 , cyclooxygenase 2 ( COX 2 ) , MLH 1 , O 6 methylguanine DNA methyltransferase ( MGMT ) , p 16 ( CDKN2A ) , and fatty acid synthase ( FASN ) . ^^^ More frequent KRAS mutations and less frequent p 16 loss and TP 53 positivity were observed in the mucinous group than nonmucinous carcinoma . 18q LOH and COX 2 overexpression were less common in the signet group than nonmucinous carcinoma . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| In esophageal cancer , there was a correlation between Cox 2 expression and wild type TP 53 in Barrett ' s esophagus ( BE ) and in adenocarcinoma , but not in squamous cell carcinoma ( P < 0 . 01 ) . ^^^ Here we show that the tumor suppressor p 53 upregulated Cox 2 in esophageal and colon cancer cell lines by inducing the binding of nuclear factor kappaB ( NF kappaB ) to its response element in the COX 2 promoter . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| COX 2 expression is suppressed by the wild type but not by the mutant tumour suppressor gene TP 53 . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| K ras codon 12 mutations were determined and immunohistochemical testing for p 16 , Tp 53 , Smad 4 , and cyclooxygenase 2 was performed . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| We investigated the association of survival with genetic polymorphisms in 10 ray repair cross complementing group 1 and group 3 ( XRCC 3 ) , xeroderma pigmentosum group D ( XPD ) , excision repair cross complementing group 1 , ligase 4 , ribonucleotide reductase , TP 53 , cyclooxygenase 2 , interleukin 6 , peroxisome proliferator activated receptor gamma , epidermal growth factor , methylene tetra hydrofolate reductase and methionine synthase . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| We report fluorescence in situ hybridization ( FISH ) and somatic cell hybrid mapping data for 13 different horse genes ( ANP , CD 2 , CLU , CRISP 3 , CYP 17 , FGG , IL1RN , IL 10 , MMP 13 , PRM 1 , PTGS 2 , TNFA and TP 53 ) . ^^^ |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35354 and P04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|