| Interacting proteins: P35240 and P49023 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P35240 and P49023 |
Pubmed |
SVM Score :0.75357908 |
| Here we report that the molecular adaptor paxillin binds directly to schwannomin at residues 50 70 , which are encoded by exon 2 . 0.75357908^^^ Paxillin binds schwannomin and regulates its density dependent localization and effect on cell morphology . 0.59131545^^^ |
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| Interacting proteins: P35240 and P49023 |
Pubmed |
SVM Score :0.0 |
| In vitro studies have identified molecules that interact with the product ( merlin or schwannomin ) , some of which ( e . g . , CD 44 and paxillin ) may play critical roles in merlin growth regulation . ^^^ |
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| Interacting proteins: P35240 and P49023 |
Pubmed |
SVM Score :0.0 |
| In Schwann cell / sensory neuron cocultures , beta ( 1 ) integrins complex with focal adhesion kinase ( FAK ) , fyn kinase , paxillin , and schwannomin in response to basal lamina adhesion . ^^^ To study the assembly of this signaling complex in Schwann cells ( SCs ) , we induced beta ( 1 ) integrin clustering on suspended cells using an immobilized antibody and recovered a complex containing beta ( 1 ) integrin , FAK , paxillin , and schwannomin . ^^^ Although C3T caused dose dependent morphological abnormalities , FAK , paxillin , and schwannomin were able to coimmunoprecipitate with beta ( 1 ) integrin . ^^^ Additionally , colocalization of FAK , paxillin , and schwannomin with beta ( 1 ) integrin in filopodia and small focal contacts remained unchanged . ^^^ |
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