| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.67444756 |
| A second mammalian gene , encoding BAP 37 , a protein with sequence similarity to prohibitin , is thought to be involved in lymphocyte function [ 9 ] . 0.67444756^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.56604816 |
| The prohibitins of Saccharomyces cerevisiae , Phb 1 and Phb 2 , have strong sequence similarity with their human counterparts prohibitin and BAP 37 , making yeast a good model organism in which to study prohibitin function . 0.56604816^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| In contrast to the nucleus , mitochondrial degradation in lens fibre cells was a rapid process and involved a relatively sharp transition between positive and negative fibre cells for two mitochondrial specific markers , BAP 37 and prohibitin . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| Using blue native electrophoresis we have demonstrated that human prohibitin and Bap 37 together form a large complex in the mitochondrial inner membrane . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| The two prohibitin proteins , Phb1p and Phb2p ( BAP 37 ) , have been ascribed various functions , including cell cycle regulation , apoptosis , assembly of mitochondrial respiratory chain enzymes , and aging . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| BAP 37 and Prohibitin are specifically recognized by an SV 40 T antigen antibody . ^^^ The two proteins were identified as BAP 37 and Prohibitin . ^^^ BAP 37 and Prohibitin are specifically recognized by PAb 419 and PAb 210 , another anti SV 40 T antigen monoclonal antibody , which has an overlapping epitope , but not by other anti SV 40 T antigen monoclonal antibodies , demonstrating the specificity of the interaction . . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| The yeast prohibitins , Phb1p and Phb2p , are close in sequence to their two human counterparts , prohibitin and BAP 37 . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| The mitochondrial prohibitin complex consists of two subunits ( PHB 1 of 32 kD and PHB 2 of 34 kD ) , assembled into a membrane associated supercomplex of approximately 1 MD . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| This screen unveiled mutations in PHB 1 and PHB 2 encoding the two subunits of the prohibitin complex , which is located to the IMM and required for the stability of mitochondrially encoded proteins . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| These include adenine nucleotide translocator 1 , the lipoyl containing E 2 subunits of pyruvate dehydrogenase and branched chain alpha ketoacid dehydrogenase and prohibitin 2 . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| In a yeast two hybrid screen using the full length Akt as bait , we found that prohibitin 2 ( PHB 2 ) specifically interacts with Akt . ^^^ Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| Two prohibitin homologues , Phb 1 and Phb 2 , assemble into a high molecular weight complex of approximately 1 . 2 MDa in the mitochondrial inner membrane , but a nuclear localization of Phb 1 and Phb 2 also has been reported . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| The deduced amino acid sequences of PhPHB 1 and PhPHB 2 , sequences that we identified in a petunia floral expressed sequence tag ( EST ) database , show high similarity to those of prohibitin 1 and prohibitin 2 proteins , respectively , reported from yeast , animals and plants . ^^^ Southern analysis suggested that these genes were members of small gene families with at least two prohibitin 1 homologs and four prohibitin 2 homologs . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| Prohibitin , which consists of two subunits PHB 1 and PHB 2 , plays a role in cell cycle progression , senescence , apoptosis , and maintenance of mitochondrial function in mammals and yeast . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| Isolation of mutations synthetic lethal to prohibitin 2 null mutants of Saccharomyces cerevisiae . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| Prohibitins in eukaryotes consist of two subunits ( PHB 1 and PHB 2 ) that together form a high molecular weight complex in the mitochondrial inner membrane . ^^^ |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35232 and Q99623 |
Pubmed |
SVM Score :0.0 |
| NA |
|