| Compared to those in adjacent normal epitheliums , the expression of 15 proteins including enolase , elongation factor Tu , isocitrate dehydrogenase , tubulin alpha 1 chain , tubulin beta 5 chain , actin ( cytoplasmic 1 ) , glyceraldehyde 3 phosphate dehydrogenase , tropomyosin isoform 4 ( TPM 4 ) , prohibitin , peroxiredoxin 1 ( PRX 1 ) , manganese containing superoxide dismutase ( MnSOD ) , neuronal protein , and transgelin was up regulated ; and the expression of five proteins including TPM 1 , squamous cell carcinoma antigen 1 ( SCCA 1 ) , stratifin , peroxiredoxin 2 isoform a , and alpha B crystalline was down regulated in cancer tissues with a statistical significance ( p < 0 . 05 ) . ^^^ |