| Interacting proteins: P35052 and P05067 |
Pubmed |
SVM Score :0.0 |
| Secreted glypican binds to the amyloid precursor protein of Alzheimer ' s disease ( APP ) and inhibits APP induced neurite outgrowth . ^^^ Glypican bound strongly to the APP affinity column . ^^^ Purified glypican bound to APP with an equilibrium dissociation constant of 2 . 8 nM and inhibited APP induced neurite outgrowth from chick sympathetic neurons . ^^^ The effect of glypican was specific for APP , as glypican did not inhibit laminin induced neurite outgrowth . ^^^ Secreted glypican may act to inhibit APP induced neurite outgrowth in vivo by competing with endogenous proteoglycans for binding to APP . . ^^^ |
|
| Interacting proteins: P35052 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35052 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35052 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|