| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| ASK forms an active kinase complex with huCdc 7 that is capable of phosphorylating MCM 2 protein . ^^^ |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| We now show this domain also mediates the association between Dbf 4 and Mcm 2 , a key Dbf4 / Cdc7 phosphorylation target . ^^^ |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| Among them , MCM 2 protein , either in a free form or in a MCM 2 4 6 7 complex , serves as an excellent substrate for huCdc 7 ASK kinase complex in vitro . ^^^ MCM 2 and 4 in the MCM 2 4 6 7 complex are phosphorylated by Cdks as well , and prior phosphorylation of the MCM 2 4 6 7 complex by Cdks facilitates phosphorylation of MCM 2 by huCdc 7 , suggesting collaboration between Cdks and Cdc 7 in phosphorylation of MCM for initiation of S phase . huCdc 7 and ASK proteins can also be phosphorylated by Cdks in vitro . ^^^ |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| Indeed , over expression of both huCdc 7 and ASK results in the elevated phosphorylation of endogenous MCM 2 protein , as manifested by appearance of the mobility shifted form on SDS PAGE , but does not cause any significant effects on cell cycle progression . ^^^ |
|
| Interacting proteins: Q9UBU7 and P33993 |
Pubmed |
SVM Score :0.0 |
| In this study , we identified DBF 4 , which encodes the regulatory subunit of a Cdk like protein kinase Cdc 7 Dbf4 , in a screen for second site suppressors of mcm 2 1 . ^^^ The dbf 4 suppressor mutation restores competence to initiate DNA synthesis to the mcm 2 1 mutant . ^^^ |
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