| Using a GST pull down assay , we determined that Smc 1 interacts physically with Mcm 7 via its N terminal and hinge regions , and Mcm 7 interacts with Smc 1 via its middle region . 1.1035921^^^ Co immunoprecipitation revealed an interaction occurring between Smc 1 and Mcm 7 , both in vitro and in vivo . 0.5800507^^^ |