| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| Replication factors MCM 2 and ORC 1 interact with the histone acetyltransferase HBO 1 . ^^^ The biochemical and genetic interactions of MYST family protein HBO 1 with two components of the replication apparatus , MCM 2 and ORC 1 , suggest that HBO 1 associated HAT activity may play a direct role in the process of DNA replication . . ^^^ |
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| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| In particular CDC 6 was found to bind strongly to ORC 1 and ORC 2 , and to MCM 7 proteins . ^^^ |
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| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| ChIP and Re ChIP colocalizes MCM 7 and ORC 1 to the same segment specifically in late G ( 1 ) . ^^^ MCM 7 is recruited to multiple sites in chromatin in S and G ( 2 ) , at which time it is not detected with ORC 1 . ^^^ |
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| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| These procedures identified > 60 MGMT interacting proteins with diverse functions including those involved in DNA replication and repair ( MCM 2 , PCNA , ORC 1 , DNA polymerase delta , MSH 2 , and DNA dependent protein kinase ) , cell cycle progression ( CDK 1 , cyclin B , CDK 2 , CDC 7 , CDC 10 , 14 3 3 protein , and p 21 ( waf1 / cip1 ) ) , RNA processing and translation ( poly ( A ) binding protein , nucleolin , heterogeneous nuclear ribonucleoproteins , A2 / B1 , and elongation factor 1alpha ) , several histones ( H 4 , H3 . 4 , and H2A . 1 ) , and topoisomerase 1 . ^^^ |
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| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| The binding of the prereplication complex proteins Orc 1 , Orc 2 , Mcm 3 , Mcm 7 , and Cdc 6 and the novel DNA unwinding element ( DUE ) binding protein DUE B to the endogenous human c myc replicator was studied by chromatin immunoprecipitation . ^^^ In G ( 1 ) arrested HeLa cells , Mcm 3 , Mcm 7 , and DUE B were prominent near the DUE , while Orc 1 and Orc 2 were least abundant near the DUE and more abundant at flanking sites . ^^^ Similarly , the signals from Orc 1 , Mcm 3 , and Mcm 7 were at background levels in cells arrested in M phase , whereas Orc 2 retained the distribution seen in G ( 1 ) phase cells . ^^^ |
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| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q13415 and P33993 |
Pubmed |
SVM Score :0.0 |
| NA |
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