| Interacting proteins: Q9P2I0 and P33240 |
Pubmed |
SVM Score :0.0 |
| To study the distribution of 3 ' cleavage factors in the nuclei of human T 24 cells , monoclonal antibodies against the CstF 64 kDa subunit and against the CPSF 100 kDa subunit were used for immunofluorescent labelling . ^^^ The RNA 3 ' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA . ^^^ CstF 64 kDa and CPSF 100 kDa were distributed in a fibrogranular pattern in the nucleoplasm and , in addition , were concentrated in 1 4 bright foci . ^^^ |
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| Interacting proteins: Q9P2I0 and P33240 |
Pubmed |
SVM Score :0.0 |
| Nuclear domains , called cleavage bodies , are enriched in the RNA 3 ' processing factors CstF 64 kDa and and CPSF 100 kDa . ^^^ |
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| Interacting proteins: Q9P2I0 and P33240 |
Pubmed |
SVM Score :0.0 |
| Here , we report that whereas DDX 1 bodies , CBs and gems are present throughout interphase , CPSF 100 containing cleavage bodies are predominantly found during S and G 2 phases , whereas CstF 64 containing cleavage bodies are primarily observed during S phase . ^^^ A striking effect on nuclear structures was observed with latrunculin B , an inhibitor of actin polymerization , resulting in the formation of needlelike nuclear spicules made up of CstF 64 , CPSF 100 , RNA , and RNA polymerase 2 . ^^^ |
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