| Interacting proteins: Q99683 and P32121 |
Pubmed |
SVM Score :0.0 |
| The upstream JNK activators apoptosis signal regulating kinase 1 ( ASK 1 ) and mitogen activated protein kinase ( MAPK ) kinase 4 were also found in complex with beta arrestin 2 . ^^^ Cellular transfection of beta arrestin 2 caused cytosolic retention of JNK 3 and enhanced JNK 3 phosphorylation stimulated by ASK 1 . ^^^ |
|
| Interacting proteins: Q99683 and P32121 |
Pubmed |
SVM Score :0.0 |
| Beta arrestin 2 acts as a scaffold to enhance signaling to JNK 3 stimulated by overexpression of the MAP 3 kinase ASK 1 or by agonist activation of the angiotensin 1A receptor . ^^^ |
|
| Interacting proteins: Q99683 and P32121 |
Pubmed |
SVM Score :0.0 |
| The AT1R translocates into clathrin coated pits and internalizes upon recruitment of beta arrestin 2 which then recruits ASK 1 and JNK 3 . ^^^ |
|
| Interacting proteins: Q99683 and P32121 |
Pubmed |
SVM Score :0.0 |
| MKP 7 dephosphorylates JNK 3 bound to beta arrestin 2 , either following activation by ASK 1 overexpression or following AT1aR stimulation . ^^^ |
|
| Interacting proteins: Q99683 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|