| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| In this study , we visualize the intracellular trafficking of beta arrestin 2 in response to activation of several distinct GPCRs including the beta 2 adrenergic receptor ( beta2AR ) , angiotensin 2 type 1A receptor ( AT1AR ) , dopamine D1A receptor ( D1AR ) , endothelin type A receptor ( ETAR ) , and neurotensin receptor ( NTR ) . ^^^ |
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| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| Agonist independent AT1AR internalization was also observed after beta arrestin 2 overexpression . ^^^ |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| Thus , upon AngII stimulation the mutant beta arrestin 2 ( K 11 , 12R ) is only transiently ubiquitinated , does not form stable endocytic complexes with the AT1aR , and is impaired in scaffolding activated ERK1 / 2 . ^^^ In contrast , a quintuple lysine mutant ( beta arrestin 2 ( K18R , K107R , K108R , K207R , K296R ) ) is impaired in endosomal trafficking in response to V2R but not AT1aR stimulation . ^^^ |
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| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| MKP 7 dephosphorylates JNK 3 bound to beta arrestin 2 , either following activation by ASK 1 overexpression or following AT1aR stimulation . ^^^ Initial AT1aR stimulation causes a rapid ( within 5 min ) dissociation of MKP 7 from beta arrestin 2 . ^^^ |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30556 and P32121 |
Pubmed |
SVM Score :0.0 |
| NA |
|