| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Citrate synthase , alpha ketoglutarate dehydrogenase and succinate dehydrogenase were wholly mitochondrial . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| It was established that already 30 60 minute ischemia causes a decrease in intensity of succinate , alpha ketoglutarate oxidation and acceptor respiration , inhibiton in the activity of the citrate cycle enzymes ; succinate dehydrogenase , alpha ketoglutarate dehydrogenase , isocytrate dehydrogenase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Activity of pyruvate dehydrogenase ( PDG ) , isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase and malate dehydrogenase was found in the extracts of the cells of Bac . polymyxa 153 , an organism producing polymyxin B . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Alpha ketoglutarate dehydrogenase is induced by glutamate or alpha ketoglutarate ; succinate dehydrogenase is repressed by malate ; and fumarase and malic enzyme are induced by fumarate and malate , respectively . ^^^ Studies on the control of enzyme activities in vitro have shown that alpha ketoglutarate dehydrogenase and succinate dehydrogenase are inhibited by oxalacetate . ^^^ Isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , and malic enzyme are inhibited at high energy charge values , whereas malate dehydrogenase is inhibited at low energy charge . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Under conditions of experimental myocardium infarction caused in dogs by ligation of the anterior descending branch of the left coronary artery , the activity of alpha ketoglutarate dehydrogenase and succinate dehydrogenase in mitochondria of the cortex , cerebellum and medulla ablongata lowers most intensively on the first and fifth day after the appearance of acute myocardium infarction . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Effect of tetrachloromethane on alpha ketoglutarate dehydrogenase and succinate dehydrogenase activity in mitochondria of rat liver under conditions of administration of polycyclic hydrocarbons ] . ^^^ The activity of the mitochondria internal membrane ensymes alpha ketoglutarate dehydrogenase and succinate dehydrogenase was studied after rats poisoning with CCl 4 . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| In cell free extracts of mycelium forming oxalate and CO 2 from added citrate the following enzymes of the tricarboxylic acid ( TCA ) cycle were identified : citrate synthase CE 4 . 1 . 3 . 7 ) , aconitate hydratase ( EC4 . 2 . 1 . 3 ) , NAD and NADP dependent isocitrate dehydrogenase ( EC 1 . 1 . 1 . 41 , 1 . 1 . 1 . 42 ) , ( alpha oxoglutarate dehydrogenase ( EC 1 . 2 . 4 . 2 ) , succinate dehydrogenase ( EC 1 . 3 . 99 . 1 ) , fumarate hydratase ( EC 4 . 2 . 1 . 2 ) , and malate dehydrogenase ( EC 1 . 1 . 1 . 37 ) . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| While laboratory experimental model of coronary heart disease ( according to Frol ' kis et al . ) is developed , activity of succinate dehydrogenase , alpha ketoglutarate dehydrogenase , Na+ , Ka ( + ) and Mg2+ ATPase decreases , but activity of lactate dehydrogenase and concentrations of lactic and pyruvic acids in the heart tissue increase . ^^^ In the liver tissue activity of succinate dehydrogenase , alpha ketoglutarate dehydrogenase , Na+ , K ( + ) and Mg2+ ATPase falls , while concentrations of lactic acid grow . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The maximal rate ( Vmax ) of some mitochondrial enzyme activities related to energy transduction ( citrate synthase , alpha ketoglutarate dehydrogenase , malate dehydrogenase , succinate dehydrogenase , NADH cytochrome c reductase , cytochrome oxidase ) and amino acid metabolism ( glutamate dehydrogenase , glutamate pyruvate transaminase and glutamate oxaloacetate transaminase ) are evaluated in non synaptic ( `` free ' ' ) and intrasynaptic mitochondria from brain hippocampus . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| This inhibition appeared to be correlated with selective inactivation of three mitochondrial key enzymes , NADH dehydrogenase , succinate dehydrogenase , and alpha ketoglutarate dehydrogenase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Activity of alpha ketoglutarate dehydrogenase ( KGDH ) and succinate dehydrogenase ( SDH ) decreased immediately after hypokinesia and remained lowered till day 18 . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Cell extracts of the organism were found to contain high activities of the following enzymes : citrate synthase , aconitase , isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , fumarase , malate dehydrogenase and pyruvate synthase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Changes in the H+ ATPase properties are accompanied by a fall in the alpha ketoglutarate dehydrogenase and succinate dehydrogenase activities and by disturbance of the liver mitochondria contractile properties . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| On hypokinesia days 30 and 45 the activity of succinate dehydrogenase ( SDH ) and alpha ketoglutarate dehydrogenase ( alpha KGDH ) decreased , that of cytoplasmatic malate dehydrogenases ( MDH ) slightly increased , and that of NADP ICDH declined . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The study of 165 rats exposed to 60 day hypokinesia demonstrated a decrease in the quantity of mitochondrial protein and a decline in the activity of mitochondrial forms of NADP isocitrate dehydrogenase ( NADP ICDH ) and NAD malate dehydrogenase ( NAD MDH ) , as well as NAD ICDH , succinate dehydrogenase ( SDH ) and alpha ketoglutarate dehydrogenase ( alpha KGDH ) . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| In addition , pyruvate dehydrogenase ( PDH ) , isocitrate dehydrogenase ( ICDH ) , alpha ketoglutarate dehydrogenase ( KGDH ) , and succinate dehydrogenase ( SDH ) activities also tended to be higher in BM . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Changes in the rates of glycolysis , glycogenolysis , activities of pyruvate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , serum glutamic pyruvic and oxaloacetic transaminases in the brain hemispheres and stem of rats exposed to 5 7 hypoglycemic comas were studied . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Citrate synthase , aconitase , isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinyl coenzyme A synthetase , succinate dehydrogenase , and fumarase were not detected in cell lysates of S . floricola ( 23 6 ) . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Only four defects of the Krebs cycle are known : fumarase deficiency , dihydrolipoyl dehydrogenase deficiency , alpha ketoglutarate dehydrogenase deficiency , and combined defects of muscle succinate dehydrogenase and aconitase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| A significant decrease was observed in the activities of isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , malate dehydrogenase , NADH dehydrogenase and cytochrome oxidase in heart mitochondria of isoproterenol administered rats . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The maximum rate ( Vmax ) of some mitochondrial enzymatic activities related to the energy transduction ( citrate synthase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , malate dehydrogenase , cytochrome oxidase ) and amino acid metabolism ( glutamate dehydrogenase , glutamate pyruvate transaminase , glutamate oxaloacetate transaminase ) was evaluated in non synaptic ( free ) and intra synaptic mitochondria from rat brain cerebral cortex . ^^^ In fact , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , malate dehydrogenase , glutamate pyruvate transaminase and glutamate oxaloacetate transaminase are lower , while citrate synthase , cytochrome oxidase and glutamate dehydrogenase are higher in intra synaptic mitochondria than in non synaptic ones . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Fusaric acid affects mitochondrial energy metabolism by at least three modes of action : ( 1 ) Inhibition of succinate dehydrogenase ( in the 10 ( 3 ) 10 ( 2 ) M range ) ; ( 2 ) inhibition of oxidative phosphorylation ( in the 10 ( 5 ) 10 ( 4 ) M range ) ; and ( 3 ) inhibition of alpha ketoglutarate dehydrogenase ( in the 10 ( 5 ) 10 ( 4 ) M range ) . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The absence of other enzyme activities of the cycle , including alpha ketoglutarate dehydrogenase , succinyl CoA synthetase , and succinate dehydrogenase also are shown . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Enzymes involved in the catabolism of proline with high activities were : proline dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , fumarase , NADP linked malic enzyme , alanine aminotransferase and malate dehydrogenase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| In this paper we report that , among the enzymes that constitute the Krebs cycle , only two are activated by aluminum : alpha ketoglutarate dehydrogenase and succinate dehydrogenase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Phosphoenolpyruvate carboxykinase , pyruvate dehydrogenase , succinate dehydrogenase , NADP ( + ) linked malic enzyme , NADH fumarate reductase , malate dehydrogenase , and alpha ketoglutarate dehydrogenase and glycerol kinase on the other hand had specific activities greater than 60 nanomoles / min / mg protein . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| High activities of most of the studied enzymes except for alpha ketoglutarate dehydrogenase ( alpha KGDH ) and succinate dehydrogenase have been estimated . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| DL alpha lipoic acid supplemented aged rats showed a decrease in the levels of lipid peroxidation and oxidized glutathione and increase in the levels of reduced glutathione , vitamins C and E and the activities of mitochondrial enzymes like isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , NADH dehydrogenase and cytochrome c oxidase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Decreased activities of TCA cycle key enzymes such as isocitrate dehydrogenase ( ICDH ) , succinate dehydrogenase ( SDH ) , malate dehydrogenase ( MDH ) and alpha ketoglutarate dehydrogenase ( alpha KGDH ) in hepatoma and surrounding tissues of hepatoma bearing rats were observed . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Another set of genes displayed a pairwise , alternating pattern of expression in response to contiguous TCA cycle enzyme defects : expression was elevated in aconitase and isocitrate dehydrogenase mutants , diminished in alpha ketoglutarate dehydrogenase and succinyl CoA ligase mutants , elevated again in succinate dehydrogenase and fumarase mutants , and diminished again in malate dehydrogenase and citrate synthase mutants . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| These effects were shown to be mediated by reversible alterations in NAD ( P ) H utilization and in the activities of specific Krebs cycle enzymes alpha ketoglutarate dehydrogenase ( KGDH ) and succinate dehydrogenase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Co administration of arsenic treated rats with ascorbic acid and alpha tocopherol showed significant reduction in the level of lipid peroxidation and elevation in the levels of ascorbic acid , alpha tocopherol , glutathione and total sulfhydryls and in the activities of isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , NADH dehydrogenase and cytochrome c oxidase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The activities of mitochondrial enzymes isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , malate dehydrogenase , NADH dehydrogenase and cytochrome C oxidase were significantly lowered in mammary carcinoma bearing rats when compared with control rats . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Non thiamine dependent enzymes such as succinate dehydrogenase ( SDH ) , succinate thiokinase ( STH ) and malate dehydrogenase ( MDH ) were altered as much or more than thiamine dependent enzymes such as the alpha ketoglutarate dehydrogenase complex ( KGDHC ) ( 21 . 5 % ) and PDHC ( 10 . 5 % ) . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The activities of the mitochondrial Krebs cycle enzymes isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase and malate dehydrogenase , and respiratory chain enzymes NADH dehydrogenase and cytochrome c oxidase were significantly reduced in both tumour and surrounding tissue of the mammary carcinoma bearing rats . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| In the present study , the activities of citric acid cycle enzymes , such as isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , and malate dehydrogenase , were found to be decreased in aged rats as well as that of electron transferring enzymes such as NADH dehydrogenase and cytochrome c oxidase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| METHODS : In the present study we have evaluated the efficacy of carnitine , a mitochondrial metabolite and lipoic acid , a potent antioxidant on the activities of the tri carboxylic acid ( TCA ) cycle enzymes like succinate dehydrogenase , malate dehydrogenase , alpha ketoglutarate dehydrogenase , Isocitrate dehydrogenase and electron transport complex 1 4 in young and aged heart mitochondria . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The mitochondrial damage in the brain was assessed by examining the levels of lipid peroxides , cholesterol , phospholipid , cholesterol / phospholipid ( C / P ) ratio , and the activities of isocitrate dehydrogenase , alpha ketoglutarate dehydrogenase , succinate dehydrogenase , malate dehydrogenase , NADH dehydrogenase , and cytochrome C oxidase . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| Decreased activities of TCA cycle key enzymes such as isocitrate dehydrogenase ( ICDH ) , succinate dehydrogenase ( SDH ) , malate dehydrogenase ( MDH ) and alpha ketoglutarate dehydrogenase ( alpha KGDH ) in lung cancer bearing animals were observed . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The activities of tricarboxylic acid enzymes such as isocitrate dehydrogenase ( ICD ) , alpha ketoglutarate dehydrogenase ( alpha KGD ) , succinate dehydrogenase ( SD ) , malate dehydrogenase ( MD ) , NADH dehydrogenase , and cytochrome c oxidase were determined in mitochondrial fraction . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| When cultured in YPD medium containing 15 % glucose under aerobic conditions , the KGD 1 ( alpha ketoglutarate dehydrogenase ) gene disrupted mutant produced a lower level of succinate than the wild type strain , while the SDH 1 ( succinate dehydrogenase ) gene disrupted mutant produced an increased level of succinate . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| A decreased trend in the activity of respiratory enzymes such as lactate dehydrogenase ( LDH ) , isocitrate dehydrogenase ( ICDH ) , succinate dehydrogenase ( SDH ) , malate dehydrogenase ( MDH ) , alpha ketoglutarate dehydrogenase ( alpha KDH ) and glutathione ( GSH ) were recorded in the hepatopancreas , ovary and gills of S . serrata for all the tested concentrations of naphthalene and the results were analyzed for their significance . . ^^^ |
|
| Interacting proteins: P31040 and Q02218 |
Pubmed |
SVM Score :0.0 |
| The activities of membrane bound phosphatases ( Na ( + ) K ( + ) ATPase , Ca ( 2+ ) ATPase , Mg ( 2+ ) ATPase and Total ATPase ) , transaminases ( alanine transaminase ( ALT ) and aspartate transaminase ( AST ) ) and mitochondrial enzymes ( isocitrate dehydrogenase ( ICDH ) , succinate dehydrogenase ( SDH ) , malate dehydrogenase ( MDH ) , alpha ketoglutarate dehydrogenase ( KGDH ) , NADH dehydrogenase , cytochrome C oxidase ) in WSSV infected tissues ( hemolymph , hepatopancreas , gills and muscle ) of Fenneropenaeus indicus were determined at intervals after WSSV infection ( 0 , 24 , 48 , 72 and after 72 h ( moribund ) ) . ^^^ |
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