| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| When hindlimb muscle succinate dehydrogenase activity and GLUT 4 content were compared for both the combined sedentary and trained groups , a significant correlation ( r = 0 . 68 ) was obtained . ^^^ |
|
| Interacting proteins: P31040 and P14672 |
Pubmed |
SVM Score :0.0 |
| In order to examine whether PHIP / IRS 1 complexes participate in the signal transduction pathway linking the IR to GLUT 4 traffic in muscle cells , L 6 myoblasts stably expressing a myc tagged GLUT 4 construct ( L6GLUT4myc ) were transfected with either wild type or dominant interfering forms of PHIP . ^^^ Whereas insulin dependent GLUT4myc membrane translocation was not affected by overexpression of PHIP , DN PHIP caused a nearly complete inhibition of GLUT 4 translocation , in a manner identical to that observed with a dominant negative mutant of the p 85 subunit of phosphatidylinositol 3 kinase ( Deltap 85 ) . ^^^ Furthermore , DN PHIP markedly inhibited insulin stimulated actin cytoskeletal reorganization , a process required for the productive incorporation of GLUT 4 vesicles at the cell surface in L 6 cells . ^^^ |
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