| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| Insulin like growth factor 1 receptor , platelet derived growth factor receptor ( PDGFR ) , TrkE , Axl , epidermal growth factor receptor , etc . , appear to be the most abundant receptor type PTKs in the thyroid ; many of which ( PDGFR , TrkE , Axl , etc . ) have never previously been demonstrated to be expressed in the thyroid . ^^^ |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| Many tyrosine kinases , such as the epidermal growth factor receptor , Her 2 / Neu , Src , and Axl , are known to play a role in oncogenic signals in transformed cells . ^^^ |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| We also report on the existence of likely dominant negative forms for many of the receptor kinases and phosphatases , including some 26 secreted decoys ( seven known and 19 novel : Alk , Csf1r , Egfr , Epha 1 , 3 , 5 , 7 and 10 , Ephb 1 , Flt 1 , Flt 3 , Insr , Insrr , Kdr , Met , Ptk 7 , Ptprc , Ptprd , Ptprg , Ptprl , Ptprn , Ptprn 2 , Ptpro , Ptprr , Ptprs , and Ptprz 1 ) and 13 transmembrane forms ( four known and nine novel : Axl , Bmpr1a , Csf1r , Epha 4 , 5 , 6 and 7 , Ntrk 2 , Ntrk 3 , Pdgfra , Ptprk , Ptprm , Ptpru ) . ^^^ |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| Subsequently , chimeric EGFR / Ufo receptors consisting of the extracellular domains of the epidermal growth factor receptor ( EGFR ) and the transmembrane and intracellular moiety of Ufo were engineered . ^^^ Competitive inhibition of substrate binding and mutagenesis experiments with EGFR / Ufo constructs revealed C terminal tyrosine 821 ( EILpYVNMDEG ) as a docking site for multiple effectors , namely PLCgamma , p 85 proteins , GRB 2 , c src and lck . ^^^ |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30530 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|