| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| NMT and c Src mRNA levels were generally elevated in a subset of human colon cancer cell lines . ^^^ |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| The NMT activity was assayed using cAMP dependent protein kinase or pp 60 ( src ) derived peptide as a substrate . ^^^ |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| The results showed that in scr / mice the effect of TCDD was less in the case of mRNA expression of PDGF ( AA ) , STAT 3 , C / EPBbeta , NMT 1 , and AP 2gamma in addition to c src as compared to scr + / + mice . ^^^ |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| Ablation of NMT 1 inhibited cell replication associated with a loss of activation of c Src and its target FAK as well as reduction of signaling through the c Raf / mitogen activated protein kinase / extracellular signal regulated kinase kinase / extracellular signal regulated kinase pathway . ^^^ |
|
| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| Using a synthetic peptide containing the first 11 amino acids of the mature pp60v src polypeptide sequence as a substrate , we probed lysates from a variety of cells and tissues for N myristyl transferase ( NMT ) activity . ^^^ Since NMT activity was detected in rabbit reticulocyte lysates , we took advantage of the translational capability of these lysates to determine the precise point during translation at which myristate is attached to pp60v src . src mRNA , transcribed from cloned 5 src DNA , was translated in reticulocyte lysates which had been depleted of endogenous myristate . ^^^ |
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| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| N Myristoylation of p56lck , a member of the Src family of protein tyrosine kinases , is essential for its proper targeting to the plasma membrane . 2 Hydroxymyristic acid ( HMA ) is an analog of myristic acid that becomes metabolically activated in cells to form 2 hydroxymyristoyl CoA , a potent inhibitor of myristoyl CoA : protein N myristoyltransferase ( NMT ) , the enzyme that catalyzes protein N myristoylation [ Paige , L . ^^^ |
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| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| To investigate whether , through Src , NMT contributes to the pathogenesis of gallbladder carcinoma , the authors investigated expression of NMT and p 53 in in situ and invasive carcinomas . ^^^ |
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| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| The enzymes NMT and MetAP play a major role in the process of myristoylation of oncoproteins including the c src family . ^^^ This is the first study demonstrating the expression of MetAP 2 , NMT , pp 60 ( c src ) , and NIP 71 in HCCLs . . ^^^ |
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| Interacting proteins: P30419 and P12931 |
Pubmed |
SVM Score :0.0 |
| During ischemia reperfusion , the degradation of c Src , which is a substrate of NMT , was observed . ^^^ These findings suggested that the Src signaling may be impaired in ischemia reperfusion owing to the altered localization of NMT from cytoplasm to nucleus . ^^^ |
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