In control mice , the expression of Gpx 1 increased and that of Gpx 3 decreased at the aortic sinus after 20 weeks of HFD , with no change in the expression of Gpx 2 , Gpx 4 , catalase , peroxiredoxin 6 , glutaredoxin 1 and 2 , or thioredoxin 1 and 2 . ^^^