| Interacting proteins: P29279 and Q07954 |
Pubmed |
SVM Score :0.91973874 |
| The identification of LRP as a receptor for CTGF was validated by several studies : 1 ) binding competition with many ligands that bind to LRP , including receptor associated protein ; 2 ) immunoprecipitation of CTGF receptor complex with LRP antibodies ; and 3 ) cells that are genetically deficient for LRP were unable to bind CTGF . 0.91973874^^^ |
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| Interacting proteins: P29279 and Q07954 |
Pubmed |
SVM Score :0.0 |
| Tyrosine phosphorylation of the LDL receptor related protein ( LRP ) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation . ^^^ |
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| Interacting proteins: P29279 and Q07954 |
Pubmed |
SVM Score :0.0 |
| Gao and Brigstock assign to CCN 2 module 3 the capacity to mediate binding to low density lipoprotein receptor related protein ( LRP ) , which was previously reported to interact with CCN 2 and to be involved in various types of signalling . ^^^ They also establish that CCN 2 binding to LRP is heparin dependent and that module 4 of CCN 2 promotes LRP independent adhesion of hepatic stellate cells . ^^^ The differential binding of CCN 2 isoforms to LRP highlights the importance of functional interactions between individual modules , and reinforces the concept that different module combinations might confer agonistic or antagonistic activities . ^^^ |
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| Interacting proteins: P29279 and Q07954 |
Pubmed |
SVM Score :0.0 |
| Possible role of LRP 1 , a CCN 2 receptor , in chondrocytes . ^^^ Exogenously added CCN 2 was incorporated into HCS 2 / 8 , which was partially co localized with LRP 1 , and targeted to the recycling endosomes and nucleus as well as the lysosomes . ^^^ |
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| Interacting proteins: P29279 and Q07954 |
Pubmed |
SVM Score :0.0 |
| NA |
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