| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CCN 3 is a founding member of the CCN ( Cyr 61 , Ctgf , Nov ) family of cell growth and differentiation regulators . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Elevated levels of cAMP induced by forskolin mimicked the effects of relaxation on the regulation of Cyr 61 , CTGF and Nov . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Another locus sharing homology with novH and corresponding to the connective tissue growth factor ( CTGF ) gene has also been mapped on chromosome 6q23 . 1 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Xnov shows 62 . 9 , 60 . 5 , 52 . 2 , 52 . 1 , 47 . 6 and 45 . 8 % identity with the chicken Nov , human NovH , human CTGF , mouse Fisp 12 , chicken Cef 10 and mouse Cyr 61 proteins , respectively . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| To compare expression of cyr61H in human tumour cell lines with that of two other structurally related genes , novH ( nephroblastoma overexpressed gene ) and CTGF ( connective tissue growth factor ) , that are likely to play a role in the control of cell proliferation and differentiation . ^^^ Expression of cyr61H , novH , CTGF , and novH was analysed by northern blotting in both human neuroblastomas and glioblastoma cell lines . ^^^ The data showed that the cyr61H gene is assigned to chromosome 1p22 . 3 and that different levels of cyr61H , CTGF , and novH mRNA have been detected in several human tumour cell lines derived from the nervous system . ^^^ Although the coding regions of cyr61H , CTGF , and novH are highly homologous , a growing body of evidence suggests that expression of these genes is regulated differentially , and that a balance between expression of these genes might represent a key element in determining the stage of differentiation and / or the malignant potential of tumour cells . . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The NOVH protein belongs to the emerging CCN [ Connective tissue growth factor ( CTGF ) , Cyr61 / Cef10 , nephroblastoma overexpressed gene ] family of growth regulators sharing a strikingly conserved multimodular organization but exhibiting distinctive functional features . ^^^ Two members of the family ( CYR 61 and CTGF ) are positive regulators of cell proliferation , whereas NOVH and two other members ( ELM 1 and RCOP 1 ) exhibit features of negative regulators of growth . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NOVH belongs to the CCN ( CTGF / CYR61 / NOV ) family of proteins , some of which have chemotactic , mitogenic , adhesive , and angiogenic properties . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| To gain insight into the role of the CCN genes in human breast carcinomas , we quantified connective tissue growth factor ( CTGF ) , WISP 1 , CYR 61 , and human NOV ( NOVH ) mRNA expression levels in samples from 44 primary breast tumors and seven normal breasts using quantitative real time PCR assay . ^^^ Overexpression of CTGF , WISP 1 , CYR 61 , and NOVH was found in 55 ( 24 of 44 ) , 46 ( 20 of 44 ) , 39 ( 17 of 44 ) , and 11 % ( 5 of 44 ) primary breast tumors , respectively . ^^^ In contrast to CTGF , WISP 1 , and CYR 61 , no significant correlation was found between NOVH expression and any of the clinical and pathological factors . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| In conclusion , our data provide evidence that novH is a new target of TGFbeta 1 ; unlike other members of the CCN ( cyr 61 , ctgf , nov ) family , however , its expression is repressed rather than induced . . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| AIMS : To analyse the similarities between the Twisted gastrulation ( TSG ) proteins known to date ; in addition , to determine phylogenetic relations among the TSG proteins , and between the TSGs and other protein families the CCN ( for example , CCN 2 ( CTGF ) , CCN 1 ( CYR 61 ) , and CCN 3 ( NOV ) ) and IGFBP ( insulin like growth factor binding protein ) families . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The CCN 3 ( NOV ) protein belongs to the CCN [ cysteine rich CYR 61 , connective tissue growth factor ( CTGF ) , nephroblastoma overexpressed gene ( Nov ) ] family of growth regulators , sharing a strikingly conserved multimodular organization but exhibiting distinctive functional features . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The proteins used in the assays were GST fused with either CCN 3 or CCN 2 ( CTGF ) and GST alone as a control . ^^^ RESULTS : The two hybrid system identified the S100A4 ( mts 1 ) calcium binding protein as a partner of CCN 3 and the use of the GST fusion proteins showed that the addition of CCN 3 and CCN 2 to G 59 glioblastoma and SK N SH neuroblastoma cells caused a pronounced but transient increase of intracellular calcium , originating from both the entry of extracellular calcium and the mobilisation of intracellular stores . ^^^ The increased intracellular calcium concentrations induced by CCN 3 and CCN 2 both involve different processes , among which voltage independent calcium channels might be of considerable importance in regulating the calcium flux associated with cell growth control , motility , and spreading . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CYR 61 ( CCN 1 ) is an extracellular matrix associated protein of the CCN family , which also includes CTGF ( CCN 2 ) , NOV ( CCN 3 ) , WISP 1 ( CCN 4 ) , WISP 2 ( CCN 5 ) , and WISP 3 ( CCN 6 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CYR 61 ( CCN 1 ) is a member of the CCN family of secreted matricellular proteins that includes connective tissue growth factor ( CCN 2 ) , NOV ( CCN 3 ) , WISP 1 ( CCN 4 ) , WISP 2 ( CCN 5 ) , and WISP 3 ( CCN 6 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| In the order of their description in the literature , CCN 1 ( CYR 61 ) , CCN 2 ( CTGF ) , CCN 3 ( NOV ) , CCN 4 ( WISP 1 ) , CCN 5 ( WISP 2 ) , and CCN 6 ( WISP 3 ) constitute a family of matricellular proteins that regulate cell adhesion , migration , proliferation , survival , and differentiation , at least in part through integrin mediated mechanisms . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CCN 3 ( NOV ) is a matricellular protein of the CCN family , which also includes CCN 1 ( CYR 61 ) , CCN 2 ( CTGF ) , CCN 4 ( WISP 1 ) , CCN 5 ( WISP 2 ) , and CCN 6 ( WISP 3 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Furthermore , T 1 also inhibits cell adhesion to other alpha 6 beta 1 ligands , including CCN 2 ( CTGF ) , CCN 3 ( NOV ) , and laminin , but not to ligands of other integrins . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Immobilized synthetic V 2 peptide supports alphavbeta 3 mediated cell adhesion ; soluble V 2 peptide inhibits endothelial cell adhesion to CCN 1 and the homologous family members CCN 2 ( connective tissue growth factor , CTGF ) or CCN 3 ( NOV ) but not to collagen . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The novel angiogenic inducer CCN 3 ( NOV , nephroblastoma overexpressed ) is a matricellular protein of the CCN family , which also includes CCN 1 ( CYR 61 ) , CCN 2 ( CTGF ) , CCN 4 ( WISP 1 ) , CCN 5 ( WISP 2 ) , and CCN 6 ( WISP 3 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| We tested this hypothesis in paired leiomyoma and myometrium by evaluating the expression of TGF beta1 / TGF beta 3 and CCN 2 , the other members of the CCN family , CCN 3 and CCN 4 , as well as fibulin 1C and S100A4 , calcium binding proteins that interact with CCNs . ^^^ The expression of these genes was menstrual cycle independent and GnRHa therapy increased the expression of CCN 2 in leiomyomas , while inhibiting CCN 3 , CCN 4 and S100A4 in myometrium ( P < 0 . 05 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The findings presented in an accompanying paper by Menzies , Parkin , and Hey regarding the survival rates and quality of life of babies with severe spina bifida ( Lancet 1985 Nov 2 ; 2 ( 8462 ) : 993 995 ) prompt the Working Group to reevaluate the ethical guidelines supporting selective treatment proposed in their 1975 report , `` Ethics of Selective Treatment of Spina Bifida ' ' ( Lancet 1975 Jan 11 ; 1 ( 7898 ) : 85 88 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CTGF is a member of a family of peptides that include serum induced immediate early gene products , a 5 src induced peptide , and a putative avian transforming gene , nov . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| During embryogenesis , cyr 61 is expressed most notably in mesenchymal cells that are differentiating into chondrocytes and in the vessel walls of the developing circulatory system . cyr 61 is a member of an emerging gene family that encodes growth regulators , including the connective tissue growth factor and an avian proto oncoprotein , Nov cyr 61 also shares sequence similarities with two Drosophila genes , twisted gastrulation and short gastrulation , which interact with decapentaplegic to regulate dorsal ventral patterning . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| On the basis of these data , we propose that CTGF represents another member of the IGFBP family ( IGFBP 8 ) and that the CTGF gene , mac25 / IGFBP 7 , nov , and cyr 61 are members of a family of low affinity IGFBP genes . ^^^ The closely related mammalian genes connective tissue growth factor ( CTGF ) gene , nov , and cyr 61 encode secreted proteins that also contain the conserved sequences and IGFBP motifs in their NH 2 termini . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The Elm 1 gene encodes a predicted protein of 367 amino acids showing approximately 40 % amino acid identity with the CCN ( connective tissue growth factor [ CTGF ] , Cyr61 / Cef10 , neuroblastoma overexpressed gene [ Nov ] ) family proteins , which consist of secreted cysteine rich proteins with growth regulatory functions . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CTGF is a member of a highly conserved family of peptides that include immediate early gene products cef 10 , cyr 61 , fisp 12 ; a putative avian proto oncogene , nov ; and a drosophila gene , twisted gastrulation , tsg , that controls medial mesoderm induction during dorsal ventral axis pattern formation , a process also controlled by TGF beta related peptides ( dpp , scw ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CYR 61 is a member of an emerging family of growth regulators that includes the human connective tissue growth factor and the chicken protooncoprotein Nov . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Connective tissue growth factor ( CTGF ) , a cytokine of the family of growth regulators comprising sef 10 , cyr 61 , CTGF and nov , has recently been described in association with scleroderma and other scarring conditions . ^^^ Connective tissue growth factor ( CTGF ) , a cytokine of the family of growth regulators comprising sef 10 , cyr 61 , CTGF and nov , has recently been described in association with scleroderma and other scarring conditions . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Homology analysis indicates that rCop 1 belongs to an emerging cysteine rich growth regulator family called CCN , which includes connective tissue growth factor , CYR 61 , CEF 10 ( 5 src inducible ) , and the product of the nov proto oncogene . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Fisp12 / CTGF is a member of a family of secreted proteins that includes CYR 61 , Nov , Elm 1 , Cop 1 / WISP 2 , and WISP 3 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CTGF L protein bears significant identity ( approximately 60 % ) to the CCN ( CTGF , Cef10 / Cyr61 , Nov ) family of proteins . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Members of the CCN ( for CTGF , cyr61 / cef10 , nov ) gene family encode cysteine rich secreted proteins with roles in cell growth and differentiation . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| NOV ( nephroblastoma overexpressed gene ) is a member of the CCN ( connective tissue growth factor [ CTGF ] , Cyr61 / Cef10 , NOV ) family of proteins . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| METHODS : Active surveillance for leptospirosis was established in an infectious disease referral hospital in Salvador , Brazil , between March 10 and Nov 2 , 1996 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| CYR 61 is a member of the emerging CCN gene family that includes CYR61 / CEF10 , CTGF / FISP 12 , and NOV ; these encode secretory growth regulatory proteins with distinct functions in cell proliferation , migration , adhesion , and survival . ^^^ We found that CYR 61 , CTGF , and NOV were expressed throughout the human central nervous system . ^^^ In contrast , CTGF and NOV expression was not altered by mAChRs neither in neuronal tissue culture nor rat brain . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Nephroblastoma overexpressed ( NOV ) is a member of the CCN family ( connective tissue growth factor , CYR 61 , and NOV ) of proteins that are involved in regulating the proliferation , differentiation , and adhesion of a variety of cell types . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Connective tissue growth factor ( CTGF ) is a member of the recently described CCN gene family which contains CTGF itself , cyr 61 , nov , elm 1 , Cop 1 , and WISP 3 . ^^^ Connective tissue growth factor ( CTGF ) is a member of the recently described CCN gene family which contains CTGF itself , cyr 61 , nov , elm 1 , Cop 1 , and WISP 3 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Whereas CYR 61 and CTGF were reported to act as positive regulators of cell growth , NOV ( nephroblastoma overexpressed ) provided the first example of a CCN protein with negative regulatory properties and the first example of aberrant expression being associated with tumour development . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Cyr 61 is a heparin binding , extracellular matrix associated protein of the CCN family , which also includes connective tissue growth factor , Nov , WISP 1 , WISP 2 , and WISP 3 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Wnt 1 induced secreted protein 1 ( WISP 1 ) is a member of the CCN ( connective tissue growth factor , Cyr 61 , NOV ) family of growth factors . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| In this study , RNA levels of two CCN ( connective tissue growth factor [ CTGF ] , Cyr61 / Cef 10 , nephroblastoma overexpressed [ NOV ] ) gene family members are shown to be upregulated in C 6 Cx43 cells : Cyr 61 and Nov . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| It is a member of the CCN family of secreted proteins , named after CTGF , cysteine rich 61 ( CYR 61 ) , and nephroblastoma overexpressed ( NOV ) proteins . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The last 5 6 years have seen the emergence of a new gene family that currently comprises CTGF , Cyr 61 , nov , elm 1 , HICP and WISP 3 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Connective tissue growth factor ( CTGF ) was recently described as a cysteine rich mitogenic peptide that is the prototypic member of the CCN family of protein including CTGF / fisp12 , cef / 10 / cyr61 and nov . ^^^ Connective tissue growth factor ( CTGF ) was recently described as a cysteine rich mitogenic peptide that is the prototypic member of the CCN family of protein including CTGF / fisp12 , cef / 10 / cyr61 and nov . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Transcription of these NoV 1 and NoV 2 cDNAs in mammalian cells led to viral RNA replication , protein synthesis , and production of infectious virus . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Connective tissue growth factor ( CTGF ) and cysteine rich 61 ( CYR 61 ) are prototypical members of the CCN family which also contains nephroblastoma overexpressed ( NOV ) and Wnt induced secreted proteins 1 , 2 and 3 ( WISP 1 , 2 , 3 ) . ^^^ Connective tissue growth factor ( CTGF ) and cysteine rich 61 ( CYR 61 ) are prototypical members of the CCN family which also contains nephroblastoma overexpressed ( NOV ) and Wnt induced secreted proteins 1 , 2 and 3 ( WISP 1 , 2 , 3 ) . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Expression of the CCN family members NOV , CTGF , CYR 61 , and WISP 1 was examined in 15 chondrosarcomas of various grades and in three enchondromas . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The CCN ( cyr 61 , ctgf , nov ) proteins are an important family of matricellular regulatory factors involved in internal and external cell signalling . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Connective tissue growth factor ( CTGF / CCN2 ) , a cysteine rich protein of the CCN ( Cyr 61 , CTGF , Nov ) family of genes , emerged from a microarray screen of genes expressed by human rhabdomyosarcoma cells . ^^^ Connective tissue growth factor ( CTGF / CCN2 ) , a cysteine rich protein of the CCN ( Cyr 61 , CTGF , Nov ) family of genes , emerged from a microarray screen of genes expressed by human rhabdomyosarcoma cells . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| We quantified CYR 61 , CTGF , WISP 1 , and NOV mRNA expression levels in samples from sixty six primary gliomas and five normal brain samples using quantitative real time PCR assay . ^^^ Overexpression of CYR 61 , CTGF , WISP 1 , and NOV occurred in 48 % ( 32 of 66 ) , 58 % ( 38 of 66 ) , 36 % ( 24 of 66 ) , and 15 % ( 10 of 66 ) of primary gliomas , respectively . ^^^ In contrast to CYR 61 and CTGF , no significant association was found between expression of either WISP 1 or NOV versus any of the pathological features . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Wnt 1 induced secreted protein 1 ( WISP 1 ) is a member of the CCN ( connective tissue growth factor , Cyr 61 , NOV ) family of growth factors . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Expressions of cysteine rich 61 , connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance . ^^^ AIM : To investigate the expression of cysteine rich 61 ( Cyr 61 ) , connective tissue growth factor ( CTGF ) and nephroblastoma overexpressed gene ( Nov ) in hepatocellular carcinoma ( HCC ) , and to evaluate the relationship between Cyr 61 , CTGF and Nov genes expression with invasion and metastasis of HCC . ^^^ Reverse transcription polymerse chain reaction ( RT PCR ) was used to detect the mRNA expression levels of Cyr 61 , CTGF and Nov genes in 31 resected specimens of hepatocellular carcinoma and para cancerous normal liver tissues semi quantitatively and the relation between their expression levels and clinical pathological parameters were compared . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| The CCN family members cysteine rich 61 ( Cyr61 / CCN1 ) , connective tissue growth factor ( CTGF / CCN2 ) and nephroblastoma over expressed ( Nov / CCN3 ) play diverse roles in cells , are known to regulate cell growth , adhesion , matrix production and migration and are involved in endocrine regulated pathways in various cell types . ^^^ Differential expression of the CCN family members Cyr 61 , CTGF and Nov in human breast cancer . ^^^ Significantly higher levels of Cyr 61 ( P = 0 . 02 ) , but low levels of CTGF and Nov , were seen in tumour tissues compared with normal tissues . ^^^ Similar to CTGF , low levels of Nov were also seen in patients with poor prognosis and mortality and with significantly decreased survival ( P = 0 . 033 and P = 0 . 0146 , respectively ) . ^^^ While fibroblasts and endothelial cells generally expressed good levels of all three CCN proteins , highly invasive MDA MB 231 cells expressed lower levels of CTGF and Nov , but higher levels of Cyr 61 , than the less invasive MCF 7 . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| All members of the Ctgf , Cyr 61 , and Nov ( CCN ) family share a high degree of sequence homology and conservation of structural motifs and domains . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| Members of the CCN family of genes include cysteine rich 61 ( CYR 61 ) , connective tissue growth factor ( CTGF ) , nephroblastoma overexpressed ( NOV ) , and Wnt induced secreted proteins ( WISP ) 1 , 2 and 3 . ^^^ Northern blot analysis revealed the presence of CYR 61 , CTGF , NOV , and WISP 1 and 2 transcripts in murine osteoblasts , but not WISP 3 transcripts . ^^^ |
|
| Interacting proteins: P48745 and P29279 |
Pubmed |
SVM Score :0.0 |
| INTRODUCTION : CCN6 / WISP3 belongs to the CCN ( Cyr 61 , CTGF , Nov ) family of genes that contains a conserved insulin like growth factor ( IGF ) binding protein motif . ^^^ |
|