| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.61338351 |
| Association of ISWI with ACF 1 , the largest subunit of CHRAC and ACF complexes , improves the efficiency of ISWI induced nucleosome mobilization by an order of magnitude and also modulates the reaction qualitatively . 0.61338351^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| ACF consists of two subunits , Acf 1 and ISWI , that function cooperatively in the ATP dependent catalysis of chromatin assembly . ^^^ Purification of the native form of Acf 1 led to the isolation of ACF comprising Acf 1 ( both p 170 and p 185 forms ) and ISWI . ^^^ Native Acf 1 did not copurify with components of NURF or CHRAC , which are other ISWI containing complexes in Drosophila . ^^^ Purified recombinant ACF , consisting of Acf 1 ( either p 185 alone or both p 170 and p 185 ) and ISWI , catalyzes the deposition of histones into extended periodic nucleosome arrays . ^^^ Notably , the Acf 1 and ISWI subunits function synergistically in the assembly of chromatin . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| WCRF is composed of two subunits , WCRF 135 , the human homolog of Drosophila ISWI , and WCRF 180 , a protein related to the Williams syndrome transcription factor . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| HuCHRAC , a human ISWI chromatin remodelling complex contains hACF 1 and two novel histone fold proteins . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| We have used a purified recombinant chromatin assembly system , including ACF ( Acf 1 + ISWI ) and NAP 1 , to examine the role of histone acetylation in ATP dependent chromatin remodeling . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| One of these complexes , xACF , consists of ISWI , Acf 1 , and a previously uncharacterized protein of 175 kDa . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| The interaction of Acf 1 with ISWI requires a DDT domain , which has been found in a variety of transcription and chromatin remodeling factors . ^^^ Thus , Acf 1 facilitates chromatin assembly via an N terminal DNA binding region with a WAC motif , a central ISWI binding segment with a DDT domain , and a C terminal region with an acidic stretch , a WAKZ motif , PHD fingers , and bromodomain . . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| SATB 1 also targets ACF 1 and ISWI , subunits of CHRAC and ACF nucleosome mobilizing complexes , to this specific site and regulates nucleosome positioning over seven kilobases . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| An ACF 1 ISWI chromatin remodeling complex is required for DNA replication through heterochromatin . ^^^ Here we provide evidence that an ACF 1 ISWI chromatin remodeling complex is required for replication through heterochromatin in mammalian cells . ^^^ ACF 1 ( ATP utilizing chromatin assembly and remodeling factor 1 ) and an ISWI isoform , SNF2H ( sucrose nonfermenting 2 homolog ) , become specifically enriched in replicating pericentromeric heterochromatin . ^^^ ACF 1 ( ATP utilizing chromatin assembly and remodeling factor 1 ) and an ISWI isoform , SNF2H ( sucrose nonfermenting 2 homolog ) , become specifically enriched in replicating pericentromeric heterochromatin . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| ACF ( ATP utilizing chromatin assembly and remodeling factor ) catalyzes the ATP dependent assembly of periodic nucleosome arrays in vitro , and consists of Acf 1 and the ISWI ATPase . ^^^ Acf 1 and ISWI are also subunits of CHRAC ( chromatin accessibility complex ) , whose biochemical activities are similar to those of ACF . ^^^ |
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| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| Two color fluorescence cross correlation spectroscopy measurements show that ACF can bind four DNA duplexes simultaneously in a complex that contains two Acf 1 and ISWI molecules . ^^^ |
|
| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28370 and Q9NRL2 |
Pubmed |
SVM Score :0.0 |
| NA |
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