| Interacting proteins: P28360 and P08047 |
Pubmed |
SVM Score :0.68907186 |
| Transcriptional autorepression of Msx 1 gene is mediated by interactions of Msx 1 protein with a multi protein transcriptional complex containing TATA binding protein , Sp 1 and cAMP response element binding protein binding protein ( CBP / p300 ) . 0.68907186^^^ |
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| Interacting proteins: P28360 and P08047 |
Pubmed |
SVM Score :0.0 |
| Combined analyses of the minimal promoter by DNase 1 footprinting , electrophoretic mobility shift assays , and super shift assays with specific antibodies revealed that 5 ' flanking regions from 161 to 154 and from 26 to 13 of the Msx 1 promoter contains an authentic E box ( proximal E box ) , capable of binding a protein immunologically related to the upstream stimulating factor 1 ( USF 1 ) and a GC rich sequence motif which can bind to Sp 1 ( proximal Sp 1 ) , respectively . ^^^ Absolute dependence of the Msx 1 minimal promoter on Sp 1 could be demonstrated by transient expression assays in the Sp 1 deficient Drosophila cell line cotransfected with Msx 1 luciferase and an Sp 1 expression vector pPacSp 1 . ^^^ |
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| Interacting proteins: P28360 and P08047 |
Pubmed |
SVM Score :0.0 |
| Computer analysis of the promoter proximal 1 . 6 kilobase pair sequence revealed a number of potentially important cis regulatory sequences ; these include the recognition elements of AP 1 , AP 2 , Msx 1 , serum response elements , SP 1 , and TCF 1 . ^^^ |
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| Interacting proteins: P28360 and P08047 |
Pubmed |
SVM Score :0.0 |
| In transient expression assays , the repressive action of Msx 3 s on Msx 1 promoter could also be reversed by co expression of exogenous Sp 1 . ^^^ |
|
| Interacting proteins: P28360 and P08047 |
Pubmed |
SVM Score :0.0 |
| NA |
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