Interacting proteins: P28360 and O75925 |
Pubmed |
SVM Score :0.66508591 |
We demonstrate that the interaction of Msx 1 with PIAS 1 , but not its sumoylation , is required for Msx 1 to function as an inhibitor of myoblast differentiation through repression of myogenic regulatory genes , such as MyoD . 0.66508591^^^ |
|
Interacting proteins: P28360 and O75925 |
Pubmed |
SVM Score :0.0 |
We show that Msx 1 conjugation to SUMO 1 in vivo is enhanced by an E 3 SUMO ligase , PIAS 1 , suggesting that sumoylation of Msx 1 is a new mechanism for modulating the molecular function of Msx 1 during organogenesis . . ^^^ |
|