Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
Molecular studies elucidated two of these genes , PAF 1 and PXR 1 . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
We also observed that peroxisome abundance was reduced fivefold in PBD cells that are defective in the PEX 1 , PEX 5 , PEX 12 , PEX 6 , PEX 10 , and PEX 2 genes . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
By transfection of PEX 2 , PEX 5 , PEX 6 , and PEX 12 cDNAs and cell fusion analysis between the CHO cell mutants , five different complementation groups ( CGs ) were identified . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
Ten mutant clones showed cytosolic PTS 2 green fluorescent protein , indicative of a defect in PTS 2 import , and were classified in five complementation groups , i . e . pex 1 , pex 2 , pex 5 , pex 14 , and group A . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
Several of the mutants obtained possessed defective genes : the PEX 2 gene was defective in SK 24 and PT 54 ; the PEX 5 gene in SK 32 and the PEX 7 gene in PT 13 and PT 32 . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
These mice were generated by targeted disruption of the PEX 2 and PEX 5 peroxisomal assembly genes encoding targeting signal receptor peroxins for the recognition and transport of a set of peroxisomal enzymes , including those of peroxisomal beta oxidation , to the peroxisomal matrix . ^^^ Analysis of esterified 22 : 6n 3 concentrations in PEX 2 / and PEX 5 / mice do not support the hypothesized requirement of peroxisomal beta oxidation in 22 : 6n 3 synthesis , as only brain , but not liver or plasma , 22 : 6n 3 levels were decreased . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
These phenotypes are also manifested in mouse models of Zellweger syndrome generated by disruption of the PEX 5 or PEX 2 gene . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
Moreover , we analyzed the ( 35 ) S Pex 5 associated complexes on peroxisomal membranes by blue native polyacrylamide gel electrophoresis . ( 35 ) S Pex 5 was in two distinct , 500 and 800 kDa complexes comprising different sets of peroxins , such as Pex 14 and Pex 2 , implying that Pex 5 transited between the subcomplexes . ^^^ |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P28328 and P50542 |
Pubmed |
SVM Score :0.0 |
NA |
|