| Interacting proteins: Q02763 and P27986 |
Pubmed |
SVM Score :0.0 |
| Deficiency in the p110alpha subunit of PI3K results in diminished Tie 2 expression and Tie 2 ( / ) like vascular defects in mice . ^^^ Phosphoinositide 3 kinase ( PI3K ) is activated by transmembrane tyrosine kinases such as vascular endothelial growth factor ( VEGF ) receptors and Tie 2 ( tunica intima endothelial kinase 2 ) , both of which are key regulators of vascular development . ^^^ These findings raise the possibility that PI3K may function as an upstream regulator of Tie 2 expression during mouse development . . ^^^ |
|
| Interacting proteins: Q02763 and P27986 |
Pubmed |
SVM Score :0.0 |
| Activated PI3K was associated with c Fes protein tyrosine kinase in these cells , but not with Tie 2 . p 70 S6 kinase ( p 70 S6K ) was activated by Ang 1 treatment , although this activation was blocked by a PI3K inhibitor , LY 294002 . ^^^ |
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| Interacting proteins: Q02763 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02763 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02763 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02763 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|