Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
VEGF signaling proceeds via autophosphorylation of VEGFR 1 and activation of the phosphatidylinositol 3 kinase ( PI3K ) pathway . ^^^ Thus , podocyte derived VEGF operates in an autocrine loop , likely through VEGFR 1 and PI3K , to stimulate alpha 3 ( 4 ) collagen production . ^^^ |
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Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
These phenotypes depend strongly on p110gamma rather than on p85alpha and were associated with decreased expression of Ang 1 , VCAM 1 , connexin 40 , and ephrinB 2 but increased expression of Ang 2 , VEGF A , VEGFR 1 , and VEGFR 2 . ^^^ |
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Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
We examined the interactions of certain proteins with a SH 2 domain with Flt 1 and KDR using the yeast two hybrid system and found that Nck , SHP 2 , PLC gamma , and PI3K p 85 bind to Flt 1 . ^^^ Nck , SHP 2 , and PI3K bind to Y 1213 of Flt 1 . ^^^ These results suggest that Nck , SHP 2 , PLC gamma , and PI3K play important roles in Flt 1 signal transduction and that Y 1213 of Flt 1 is a major binding site of PI3K , Nck , and SHP 2 . . ^^^ |
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Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
The expression of fms like tyrosine kinase ( Flt ) 1 , a vascular endothelial growth factor ( VEGF ) receptor , was enhanced in AMF expressing tumors dependent on protein kinase C and phosphatidylinositol 3 kinase ( PI3K ) activation ; meanwhile kinase insert domain containing receptor , another receptor of VEGF , was not . ^^^ |
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Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P17948 and P27986 |
Pubmed |
SVM Score :0.0 |
NA |
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