| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| ERK activation through both TPalpha and TPbeta was dependent on PKA and phosphoinositide 3 kinase ( PI3K ) class 1 ( A ) , but not class 1 ( B ) , and was modulated by Harvey Ras , A Raf , c Raf , and Rap1B / B Raf and also involved transactivation of the epidermal growth factor receptor . ^^^ |
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| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| In this study , the effects of activated Raf ( Raf 1 , A Raf and B Raf ) and PI3K / Akt proteins on abrogation of cytokine dependence in FL5 . 12 hematopoietic cells were examined . ^^^ |
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| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| Expression of a partially activated A Raf mutant resulted in decreased tyrosine phosphorylation of the PDGFR , specifically on Y 857 ( autophosphorylation site ) and Y 1021 ( phospholipase Cgamma 1 ( PLCgamma 1 ) binding site ) , but not the binding sites for other signalling proteins ( Nck , phosphatidylinositol 3 ' kinase ( PI3K ) , RasGAP , Grb 2 , SHP ) . ^^^ Activated A Raf expression also altered the activation of PLCgamma 1 , and p 85 associated PI3K . ^^^ Thus , A Raf can regulate PLCgamma 1 signalling via a PDGFR dependent mechanism and may also regulate PI3K signalling via a PDGFR independent mechanism . . ^^^ |
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| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| In microcystin transformed cells , PI3K , MAPKAPK 2 , Akt , cyclin D 1 and cyclin D 3 in the Akt pathway ; IQGAP 2 , RabGTPase , Rap1GAP , RasGAP , R Ras , Krev 1 and TC 21 of the Ras GTP / GDP protein family ; and A Raf , B Raf and PAK in the Ras / MAPK pathway were all markedly upregulated . ^^^ |
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| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|