| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| Other downstream effectors of the TCR / CD3 transduction machinery , such as phosphatidylinositol 3 kinase p85alpha , p 59 ( fyn ) , linker for activation of T cells ( LAT ) , and phospholipase C gamma 1 , are not affected . ^^^ |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| Significant attenuation of CRP induced tyrosine phosphorylation in known PI3K effectors such as Btk , Tec , PKB / Akt , and phospholipase Cgamma 2 were observed with p85alpha / platelets , whereas no alteration was noted in upstream molecules of Syk , LAT , and SLP 76 . ^^^ |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| The activated kinases then in turn phosphorylate and activate other enzymes [ phospholipase Cgamma ( PLCgamma ) isoforms , phosphatidylinositol 3 kinase ( PI3K ) isoforms , protein kinase C ( PKC ) isoforms , Bruton ' s tyrosine kinase ( Btk ) and others ] , adaptors [ linker for activation of T cells ( LAT ) , Cbl , Grb 2 and others ] and GTP exchange factors / GTPases ( Vav , Ras , Rho , and others ) , and subsequently induce the mobilization of stored and extracellular Ca ( 2+ ) . ^^^ |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| The phosphatidylinositol 3 kinase ( PI3K ) selective inhibitor wortmannin , and mouse platelets deficient in Lyn , Src , Syk , Src homology 2 ( SH 2 ) domain containing leukocyte protein 76 ( SLP 76 ) , phospholipase Cgamma 2 ( PLCgamma 2 ) , linker for activation of T cells ( LAT ) , or Fc receptor gamma chain ( FcRgamma chain ) were used for these studies . ^^^ |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P27986 |
Pubmed |
SVM Score :0.0 |
| NA |
|