| Interacting proteins: P11166 and P27797 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11166 and P27797 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11166 and P27797 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11166 and P27797 |
Pubmed |
SVM Score :0.0 |
| In both PM and MsM , we measured the total number of glucose transporters ( Ro ) , GLUT 4 , and GLUT 1 . ^^^ |
|
| Interacting proteins: P11166 and P27797 |
Pubmed |
SVM Score :0.0 |
| The glut 1 glucose transporter interacts with calnexin and calreticulin . ^^^ Thus , our data show that both calnexin and calreticulin with Glut 1 in a glycosylation dependent manner . . ^^^ |
|
| Interacting proteins: P11166 and P27797 |
Pubmed |
SVM Score :0.0 |
| Using RNA mobility shift , UV cross linking , and in vitro degradation assays , followed by mass spectrometric analysis , we identified calreticulin as a specific destabilizing trans acting factor that binds to a 10 nucleotide cis acting element ( CAE ( 2181 2190 ) ) in the 3 ' untranslated region of GLUT 1 mRNA . ^^^ Pure calreticulin accelerated the rate of GLUT 1 mRNA probe degradation in vitro , whereas overexpression of calreticulin in vascular cells decreased significantly the total cell content of GLUT 1 mRNA and protein . ^^^ These data suggest that CAE ( 2181 2190 ) calreticulin complex , which is formed in VSMC and VEC exposed to hyperglycemic conditions , renders GLUT 1 mRNA susceptible to degradation . ^^^ |
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