| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact low levels of high density lipoprotein ( HDL ) cholesterol are as much a risk factor for CAD as high LDL cholesterol . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , one in three women die from CAD in this country . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , the majority of patients with CAD are unlikely to achieve their treatment goals with monotherapy . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , patients with MF had a significantly higher prevalence of CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , patients with CKD are often excluded from randomized trials that compare different treatment strategies for CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , ADA may play a key role in the immunity , inflammation and other aspects of CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| That these metabolic abnormalities were not observed in all 1 patients may have been related to methodology , the random distribution of CAD , and the fact that the chemical composition of the CS blood reflects the metabolic balance of both well oxygenated and ischemic areas of the myocardium . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The important role of thrombogenesis in CAD is supported by the fact that initial high levels of plasma fibrinogen , coagulation factor 7 ( VIIc ) , and plasminogen activator inhibitor ( PAI 1 ) are all independent risk factors for CAD or recurrent myocardial infarction as found in multivariate analyses of epidemiological studies . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact we observed during surgical reperfusion of coronary artery disease ( CAD ) patients , a prolonged and sustained release of oxidized glutathione ; the degree of oxidative stress was inversely correlated with recovery of mechanical and haemodynamic function . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The fact that past antihypertensive treatment has not focused on these metabolic abnormalities , and indeed may have exacerbated them , could help explain why it has been difficult to show that lowering blood pressure decreases the risk of CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact digitalis modifies in normals the pattern of the left ventricular filling phase whereas it induces an untoward increase in the middle and end diastolic pressure in CAD patients . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The clinical relevance of these findings lies in the fact that there is an increasing clinical and laboratory evidence of a pathogenic role of catecholamines in coronary artery disease ( CAD ) and that some of these neuroendocrine correlates might actually be the mediators of the risk of CAD conferred by the Type A behavior pattern . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| We conclude that the reported association between earlobe crease and CAD is due to the fact that the prevalence of earlobe crease and CAD each increase with age . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| We confirmed the fact that angina is often not associated with CAD , and that CAD is often present in the absence of angina . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| Differences in the incidence of fatal myocardial infarction within five years after operation between a group of 116 patients who had no clinical evidence of CAD and a group of 209 patients suspected to have CAD attained statistical significance ( p less than 0 . 1 ) despite the fact that 67 patients suspected to have CAD eventually underwent myocardial revascularization . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The fact that only 4 % of patients without obstructive CAD have the ECG syndrome of septal fibrosis indicates the usefulness of the syndrome in identifying a subset of angina pectoris patients with advanced CAD of the proximal LAD and diffuse left ventricular hypoperfusion . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The CaM binding domain of CaD also showed similar , but less dramatic , spectral changes ; this is in agreement with the fact that it binds to CaM with lower affinity and a shorter alpha helix . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| This is of considerable importance to African Americans since African Americans have one of the world ' s highest CAD mortality rates coupled with the fact that obesity is extremely prevalent in this population . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| Because of the fact that elevated plasma levels of Lp ( a ) have been shown to be an independent risk factor for coronary artery disease ( CAD ) , we determined plasma Lp ( a ) levels in CAD for Turkish population , and compared them with previous findings of some developed countries . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| Asian Indians have the highest rates of coronary artery disease ( CAD ) of any ethnic group studied , despite the fact that nearly half of this group are life long vegetarians . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| These data suggest that , in patients with CAD , other factors beyond hydraulic effects of epicardial coronary stenosis , could modulate rMBF regulation ; in fact : 1 ) myocardium perfused by angiographically normal coronary artery shows reduced values of both resting rMBF and coronary reserve ; 2 ) myocardium supplied by stenotic vessel maintains a residual vasodilating capability despite a reduced baseline perfusion . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| These findings point to the fact that CaD is not entirely heat stable ; the C terminal CaM binding regions and the N terminal actin binding region are possibly affected by heat treatment . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The fact that an increased blood insulin level is observed in patients with coronary artery disease ( CAD ) confirms the hypothesis that insulin promotes the development of atherosclerosis . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The vitamin E concentrations were in fact significantly higher in CAD patients , and did not appear to protect the ubiquinol from increased oxidation due to free radical reactions . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , lower serum iron levels were associated with an increased risk of CAD , cardiovascular disease , and all cause mortality . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| A greater appreciation for the importance of this fact and regular use of secondary prevention strategies , including aggressive use of HMG CoA reductase inhibitors or other lipid lowering agents to reduce cholesterol levels , are clearly indicated for diabetic patients with CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| This indicates that patients who develop CAD had higher levels of circulating LDL IC , a fact that could not be deduced from the measurement of free oxLDL antibody concentrations . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , of all putative target genes thought to be activated by c Myc , only the Cad gene showed loss of growth regulation in rat cells nullizygous for c Myc . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| A lower detection rate of coronary artery disease ( CAD ) has been reported for SPECT imaging in women , despite the fact that similar numbers of women and men die each year of heart disease . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| DISCUSSION : The significantly higher increase in mean plasma levels of t PA activity and t PA antigen after VO compared to ES in both groups might be explained by the fact that CAD induced symptoms in the patients during ES thus permitting only 80 % of their age , sex , and body mass index related optimal work load . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The low specificity of myocardial scintigraphy probably relates to the fact that this method traces perfusion abnormalities , not necessarily caused by epicardial CAD , possibly due to microvascular disease and not causing obvious wall motion abnormalities . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| Combined AVR with CABG is recommended to avoid risky secondary operation in patients of CAD and AS , even if one of which is relatively mild , because of the fact that operative and late results of the combined surgery are satisfactory . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| This fact , the overall lower incidence of and the 10 15 year retarded occurrence of CAD in women , has led to the controversially discussed question whether menopause is a risk factor for CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| Substitution of Cys 60 and Cys 7 with non ligating residues specifically abrogates metal dependent negative regulation of cad O / P binding , despite the fact that C60G and C7G CadCs maintain high affinity for metals in altered coordination complexes . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The systemic nature of the disease is reflected in the fact that individuals with PAD or carotid artery disease are more likely to have CAD than those without . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The fact that human error is such a significant obstacle makes mammography screening an ideal application for computer aided detection ( CAD ) systems . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The fact that the low molecular mass proteins do not affect contractility in this model system indicates that our methods for reversible modulation of the content of CaP and CaD may provide a valuable tool for studying the thin filament based regulation of contractility . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In our opinion , it is mandatory to take into account : 1 ) what chest pain really means in women ; 2 ) the fact that there are gender differences : women have a different biological and hormonal status , lifestyle , and perception of the disease ; 3 ) that there is a different approach of the physicians to a woman with possible or suspected CAD . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The fact that traditional risk factors only account for approximately two thirds of cases of coronary artery disease ( CAD ) has stimulated increasing interest in the relationship between CAD and psychosocial factors . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| Prevalence of S 2 allele in normal controls and CAD patients were comparable , despite the fact that mean TG level was significantly higher in patients . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| These findings underline the fact that conclusions based on research performed on men with CAD may not be valid for women and that more gender related research is needed . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| CONCLUSIONS : Despite the fact that some patients with OSA may experience nocturnal ischemia , this study shows that patients with severe OSA and coexisting CAD do not have nightly episodes of myocardial injury detectable by the current generation cardiac troponin T assay . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| The incidence of sudden cardiac death can be reduced significantly with prevention ( nutrition , prevention of CAD ) and one attention should be drawn to the fact even in the future . . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , within the CAD group , regional MIBG WO was lower in reference than in damaged segments ( 38+ / 21 % vs 46+ / 19 % , p < 0 . 05 ) . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| However , the fact that CAD remains the major cause of death in North America and Europe demonstrates the need for novel , complementary diagnostic strategies . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| In fact , epidemiological studies have suggested that elevated serum ferritin levels are associated with an increased risk of CAD and myocardial infarction ( MI ) , though inconsistent results were obtained in some other studies . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND : While much of the gender difference in the treatment of coronary artery disease ( CAD ) results from the fact that the women being treated are older and have more comorbidities , it remains to be established whether a true gender bias exists . ^^^ |
|
| Interacting proteins: Q9Y5B9 and P27708 |
Pubmed |
SVM Score :0.0 |
| CONCLUSIONS : Tacrolimus shows a beneficial effect on CAD ; this could be attributed to the fact that CAD is characterized by a lymphohistiocytic infiltrate producing a chronic eczema and that tacrolimus blocks the activation of lymphocytes and other immune system cells , also inhibiting the release of mediators from cutaneous mast cells and basophils . . ^^^ |
|