| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| Based on these data and with a view to studying the effects of premature ventricular contractions ( PVCs ) on the cerebral circulation in humans , CBF was measured using the 133 Xenon inhalation method in 24 age matched human controls ( group A 1 : age 58 . 5 + / 6 . 2 years ; group A 2 : 52 . 2 + / 7 . 8 years ) in nine coronary artery disease ( CAD ) patients without PVCs ( B ) , in 11 CAD patients with frequent PVCs ( > 300 . h 1 ) ( C ) and in nine patients , after exclusion of CAD by angiography , also with frequent PVCs ( > 300 . h 1 ) ( D ) . ^^^ The significant reduction of CBF in CAD patients with frequent PVCs suggests that arrhythmias have a significant impact on CBF . ^^^ Non CAD patients with frequent PVCs did not show significant CBF decreases in comparison with controls . ^^^ One can hypothetize that an impairment of electrical postextrasystolic potentiation , due to premature ventricular depolarization , and hence myocardial dysfunction leads to CBF reduction in CAD patients . ^^^ The CBF reduction with CAD could also reflect concomitant coronary and cerebral arteriosclerosis . . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| No difference in hemodynamics , coronary blood flow ( CBF ) , coronary vascular resistance ( CVR ) , or coronary artery diameter ( CAD ) was observed at baseline between the groups . ^^^ In group 1 , intracoronary ET 1 significantly decreased CBF and CAD in association with an increase in CVR . ^^^ The percentage decrease in CBF and CAD in the group that received ET 1 and the ET A receptor antagonist ( group 2 ) was significantly less than that in the group that received ET 1 alone ( group 1 ) ( 12 + / 3 % versus 48 + / 6 % [ P < . 001 ] and 4 . 6 + / 0 . 8 versus 1 . 0 + / 0 . 3 [ P < . 05 ] , respectively ) . ^^^ There was no significant effect on CBF , CVR , or CAD in the group receiving sarafotoxin alone ( group 3 ) . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| To determine the accuracy of measurement of CFR using average peak velocity ( APV ) with Doppler guidewire , we investigated the influence of intracoronary papaverine on coronary flow velocity and coronary arterial diameter ( CAD ) and examined the correlation between CFR derived using APV and that derived using coronary blood flow ( CBF ) in 26 patients with normal coronary arteries . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| Increases in CBF to atrial pacing are inversely related to serum total cholesterol and are not related to the angiographic presence of atherosclerosis in patients with mild CAD . . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| The coronary artery diameter ( CAD ) was measured by quantitative angiography and the coronary blood flow ( CBF ) was calculated using coronary flow Doppler measurements . ^^^ RESULTS : In vivo , intracoronary administration of bFGF increased the CBF by 33 + / 33 % and the CAD by 12 + / 5 % at baseline , but reduced the CBF by 45 + / 8 % and the CAD by 14 + / 6 % after 10 weeks of a high cholesterol diet . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| At 10 weeks , ET 1 resulted in an accentuated decrease in coronary blood flow ( CBF ) and coronary artery diameter ( CAD ) compared with baseline ( 88+ / 6 % versus 45+ / 9 % , P < . 05 , and 77+ / 14 % versus 18+ / 8 % , P < . 05 , respectively ) and an increase in coronary vascular resistance ( CVR ) ( 242+ / 18 % versus 110+ / 17 % , P < . 05 ) ; ET receptor density and binding affinity in epicardial coronary arteries were unchanged . ^^^ The effect of L NMMA on CBF , CAD , and CVR was attenuated at 10 weeks ( 7+ / 8 % versus 48+ / 4 % , 2+ / 3 % versus 17+ / 5 % , and 16+ / 10 % versus 125+ / 32 % ; each P < . 05 ) . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| In patients with normal coronary arteries ( n = 29 ) or with coronary artery disease ( CAD ; n = 26 ) , coronary blood flow ( CBF ) and epicardial coronary artery diameter after intracoronary administration of 50 microg nitroglycerin or 0 . 5 mg nicorandil were measured , before and after the intravenous infusion of saline or 100 mg / kg of N acetylcysteine ( NAC ) . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| After 10 weeks of cholesterol feeding , intracoronary pinacidil resulted in a significant increase in coronary blood flow ( CBF ) and coronary artery diameter ( CAD ) compared to the normolipidemic state ( 111+ / 10 versus 59+ / 12 % , and 6+ / 1 . 1 versus 2 . 7+ / 1 . 0 % , respectively , P < 0 . 05 for both comparisons ) , whereas intracoronary glibenclamide resulted in a significant decrease in CBF and CAD compared to the normolipidemic state ( 17+ / 5 versus 5+ / 6 % , and 0 . 8+ / 1 . 4 versus 3 . 6+ / 1 . 6 % , respectively , P < 0 . 05 for both comparisons ) . ^^^ The effect of intracoronary LNMMA on CBF and CAD was significantly attenuated after 10 weeks of cholesterol feeding as compared to the normolipidemic state ( 47+ / 5 . 4 versus 0 . 8+ / 6 . 8 % , and 19 . 4+ / 5 . 7 versus 2 . 3+ / 3 . 3 % , respectively , P < 0 . 05 for both comparisons ) . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| METHODS : To investigate the effect of sarpogrelate on the microcirculation in CAD , we measured CBF in 15 patients with CAD but no significant stenosis in the left anterior descending artery ( LAD ) . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVES : We evaluated the effect of therapy with folic acid and cobalamin on coronary endothelial function , expressed as a change in volumetric coronary blood flow ( CBF ) , in hyperhomocysteinemic patients with coronary artery disease ( CAD ) . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVE : To evaluate the value of quantitative real time myocardial contrast echocardiography ( RT MCE ) combined with low dose dobutamine stress test in the detection of coronary artery disease ( CAD ) , and to assess the contribution of collateral blood flow ( CBF ) to myocardial perfusion . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| This study was aimed at evaluating the association between C reactive protein levels and endothelium dependent and endothelium independent coronary blood flow ( CBF ) responses in non culprit arteries of patients with CAD . ^^^ |
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| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03701 and P27708 |
Pubmed |
SVM Score :0.0 |
| NA |
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