| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| Xenopus cyclin A 1 can associate with Cdc 28 in budding yeast , causing cell cycle arrest with an abnormal distribution of nuclear DNA . ^^^ The induction of cyclin A 1 expression in yeast caused cell cycle arrest with an abnormal distribution of nuclear DNA to the daughter bud . ^^^ |
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| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| Our results indicate that Xenopus ORC and Cdc 2 10 cyclin A 1 physically interact and demonstrate a physical link between an active cyclin dependent kinase and proteins involved in the initiation of DNA replication . . ^^^ |
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| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| These proteins link the cyclin A 1 CDK2 complex to diverse cellular processes such as DNA repair , signaling , and splicing . ^^^ |
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| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| The cyclin A 1 CDK2 complex regulates DNA double strand break repair . ^^^ To unravel a potential role of cyclin A 1 in DNA repair , we performed a yeast triple hybrid screen and identified the Ku 70 DNA repair protein as a binding partner and substrate of the cyclin A 1 CDK2 complex . ^^^ DNA double strand break ( DSB ) repair was deficient in cyclin A 1 / cells . ^^^ These findings establish a novel function for cyclin A 1 and CDK 2 in DNA DSB repair following radiation damage . . ^^^ |
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| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| As proof of principle , we illustrate MEP using assays of p 16 and cyclin A 1 promoters in a methylated DNA dilution matrix and also in a clinical setting using paired saliva and oral tumour specimens . ^^^ In our clinical example , MEP of saliva derived DNA was more sensitive than standard non methylation specific pyrosequencing as illustrated using p 16 and cyclin A 1 promoter methylation assays . . ^^^ |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P78396 |
Pubmed |
SVM Score :0.0 |
| NA |
|