| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| The results indicate : ( 1 ) after an initial heat shock , transcription of the heat shock genes by RNA polymerases 2 and 3 becomes desensitized to further heat shock , and the heat induced DNA binding activity of the HSF is lost , ( 2 ) if accumulation of heat shock gene products is inhibited , the desensitizing effect of a prior heat shock is removed , and ( 3 ) transcription of the hsp70 . 1 and B 2 genes apparently involves different mechanisms , with hsp70 . 1 employing the HSF and the B 2 gene using a separate , heat activated transcriptional mechanism . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| One region contains two tandemly arrayed HSP 70 sequences , designated HSP 70 1 and HSP 70 2 , separated by approximately 8 kb of DNA . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| A DNA segment from the 5 ' region of Hsp70 . 2 hybridized to a 2 . 7 kb transcript with a temporal pattern of expression in mouse spermatogenic cells similar to the P 70 protein . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| DNA polymorphisms in two transcription control elements ( SP 1 and TATA box ) of porcine HSP70 . 2 gene detected by allele specific PCR . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| The coincidence of repression of HSP70 . 1 transcription with the second round of DNA replication was not found for other transcription dependent polypeptides synthesized at the 2 cell stage . . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Polymorphic DNA markers within the cloned region were used to map the cleft palate susceptibility 1 ( Cps 1 ) locus to the interval between Hsp70 . 1 and BAT 6 ( valyl tRNA synthetase ) . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Furthermore , analysis of nuclei and genomic DNA indicated that the failure of meiosis in Hsp 70 2 / mice was coincident with a dramatic increase in spermatocyte apoptosis . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| To clarify the relationship of the hsp 70 2 gene to SLE in African Americans , genomic DNA from 46 patients and 42 appropriately matched control subjects was analyzed for an RFLP of the hsp 70 2 gene using the probe pH2 . 3 and the restriction endonuclease PstI , which identifies alleles of 8 . 5 and 9 . 0 kb . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| The HSP 70 1 promoter alleles were defined by oligonucleotide typing of polymerase chain ( PCR ) amplified genomic DNA . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Construction of cDNA library from liver RNA of heat shocked rats and DNA sequence analysis of the clone containing the 3 ' end untranslated region ( 3 ' UTR ) of the heat inducible gene hsp70 . 2 . cDNA library constructed from liver RNA of rats subjected to hyperthermia was used to isolate divergent 3 ' end untranslated regions ( 3 ' UTR ) of heat inducible hsp70 . 1 and hsp70 . 2 genes . ^^^ As a result of a double selection procedure with the use of DNA DNA hybridization and PCR analysis 9 clones containing cDNA sequences derived from the 3 ' UTR of the hsp70 . 2 gene were selected . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| To examine the role of DNA loci within the human leukocyte antigen ( HLA ) region and insulin dependent diabetes mellitus ( IDDM ) , we studied fine mapping of HSP 70 2 gene . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| A DNA region containing several repetitive motifs has been detected about 1 . 9 kbp upstream of the transcription unit of the rat stress inducible hsp 70 . 1 gene . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| By taking mRNAs of beta actin , heat shock protein HSP70 . 1 and ribosomal protein S 16 as experimental models , we demonstrate the effectiveness of genomic DNA digestion by DNase 1 Mn++ and of DNase 1 heat denaturation and the quantitative properties of our method . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Propidium iodide staining and cytophotometry indicated that the average DNA content of nuclei in MN 7 positive cells in Hsp 70 2 ( / ) mice was usually about twice , or occasionally the same as , that of nuclei in round spermatids of wild type mice . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| The frequency of the C allele of the HSP 70 1 , characterized by the intermediate electrophoretic mobility of DNA , was significantly increased among CD patients ( 64 . 5 % vs 37 . 2 % . p < 1 10 10 ( 7 ) ) . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Genomic DNA isolated from 55 boars ( 41 Duroc , nine Landrace , and five Yorkshire ) was subjected to PCR amplification of the 5 ' flanking region of HSP70 . 2 . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| The study focused on in situ analysis of the testicular cell DNA fragmentation and on the possible relationship between Hsp 70 2 expression and germ cell apoptosis . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Upregulated mRNAs included heme oxygenase 1 ( HO 1 ) , 8 oxoguanine DNA glycosylase 1 ( OGG 1 ) , glutathione reductase ( GSR ) , cyclin dependent kinase inhibitor 1A ( CDKN 1 [ p 21 ( waf 1 ) ] ) and Mn+ superoxide dismutase precursor ( SOD 2 ) ; while cytochrome P 450 1A1 ( CYP1A1 ) and heat shock 70kD protein 1 ( HSPA1A ) were downregulated . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| In this study , in situ analysis of cell DNA fragmentation and expression of Hsp 70 2 in TU treated monkey testes were compared with the normal testes . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| METHODS : To detect the HSP 70 1 gene mRNA , total RNA was isolated and amplified by RT PCR , and the sequence was confirmed in all five patients by DNA direct sequencing analysis . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| We have investigated the association of polymorphisms 110 A / C , +190 G / C , +1267 A / G , +2074 G / C , and +2437 G / C in the 5 ' and coding regions of the HSP 70 1 , HSP 70 2 , and HSP 70 hom genes with the risk of PD by screening DNA samples from 274 PD patients and 183 controls in assays based on the polymerase chain reaction . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| Exposure to IR led to more residual chromosome aberrations , radioresistant DNA synthesis ( a hallmark of genomic instability ) , increased cell killing , and enhanced IR induced oncogenic transformation in Hsp70 . 1 / 3 ( / ) cells . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| To assess if the efficacy of E 7 based DNA vaccines could be increased by combination of various fusion genes , we combined the HSP70 . 1 fusion genes ( i . e . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| To evaluate the association between HSPA1A G ( 190 ) C , HSPA1B A ( 1267 ) G and TLR 4 A ( 299 ) G polymorphisms and allograft survival we analyzed DNA of patients with long term renal graft function over 15 years ( Tx 15 ) , consecutively transplanted recipients ( Tx ) , patients with acute rejection and healthy controls . ^^^ |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P27695 and P08107 |
Pubmed |
SVM Score :0.0 |
| NA |
|