| In this report , we demonstrate that SRC 1 , NCoA 2 , and p / CIP are capable of independently enhancing TCDD dependent induction of a luciferase reporter gene by the AHR / ARNT dimer . ^^^ We demonstrate by coimmunoprecipitation and by a reporter gene assay that SRC 1 and NCoA 2 but not p / CIP are capable of interacting with ARNT in vivo after transient transfection into mammalian cells , while AHR is capable of interacting with all three coactivators . ^^^ |