| Interacting proteins: P15976 and P27361 |
Pubmed |
SVM Score :0.0 |
| Moreover , GATA 1 did not interact with PKC zeta but interacted with ERK 1 , which was constitutively activated and accumulated in the nucleus of U 937 zetaJ . ^^^ However , ERK 1 phosphorylation inhibition by PD 098059 did not influence either GATA 1 phosphorylation or GATA 1 / ERK1 interaction . ^^^ Collectively , these results suggest a model in which PKC zeta induces MEK dependent ERK 1 activation , ERK 1 translocation to the nucleus , GATA 1 / ERK1 interaction and ERK 1 independent GATA 1 phosphorylation resulting in GATA 1 accumulation . ^^^ |
|
| Interacting proteins: P15976 and P27361 |
Pubmed |
SVM Score :0.0 |
| Furthermore , treatment of PANC 1 cells with protein kinase C ( PKC ) inhibitors , GF 1 and Ro 31 8220 , completely abrogated NT induced ERK 1 and ERK 2 activation , and significantly attenuated NT induced c Raf 1 stimulation . ^^^ |
|
| Interacting proteins: P15976 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
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